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Explore the evolution of life from simple organic molecules to complex cells, including the impact of antibiotic resistance on bacteria evolution. Discover the history of life's origin, from disproving spontaneous generation to the endosymbiotic theory. Learn about the Russian prison system's role in combating TB and the consequences of antibiotic misuse on disease resistance. Use natural selection theory to understand the rising antibiotic resistance and why a drug-resistant TB strain in Russia is concerning. Delve into biogenesis, primordial soup hypothesis, and the evolution of cells. Access relevant materials for further discussion at PBS and McGraw-Hill websites.
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Evolution Change in a population over time.
Why is the Russian prison system considered to be "ground zero" in the fight against TB? • What is responsible for the evolution of TB strains that are resistant to multiple drugs? • How does the misuse of antibiotics affect the evolution of disease-causing bacteria? Use the theory of natural selection to explain the growing resistance to antibiotics. • Why should we care about a resistant strain of TB in Russia?
Anwer questions while watching video. • http://www.pbs.org/wgbh/evolution/educators/lessons/lesson6/act1.html • Discussion. • http://www.pbs.org/wgbh/evolution/educators/teachstuds/unit6.html
The Origin of Life • Spontaneous generation – life arises from nonlife • Redi – tested idea that flies spontaneously come from rotting meat. -Not everyone was convinced of his findings.
Needham – Roman Catholic Theologian -Heated chicken and corn broths and poured them in a covered flasks. -The flasks cooled and microorganisms had grown. -Needham believed the microorganisms grew because of spontaneous generation. • Spallanzani – disagreed with Needham. - Suggested Needham’s broth had supported growth because they had been contaminated before being sealed and heated.
The Origin of Life • Louis Pasteur’s experiment • disproved spontaneous generation(mid 1800’s) • Flask 1 – only air was allowed to contact sterile nutrient broth • No microorganisms grew • Flask 2 – air and microorganisms were allowed to contact the broth. • Microorganisms grew • Theory of biogenesis – only living organisms can produce other live orgaisms.
Which came first, the chicken or the egg? • Biologists have accepted the concepts of biogenesis for more than 100 years • Biogenesis does not answer the question of how life began on Earth • No one will ever know for certain how life began on earth. We can only make hypotheses about conditions on early Earth.
Primordial Soup • Step 1: simple organic molecules must have formed (molecules that contain carbon) • Step 2: Simple organic molecules must have become organized into complex organic molecules (proteins, carbohydrates, and nucleic acids) • Hypothesized - life began in the oceans • Energy from sun and lightning triggered chemical reactions to produce small organic molecules from substances in the atmosphere • 1953 Miller and Urey (American) – replicated conditions in the lab and produced amino acids, sugars, and other molecules
The next step… • How did we get from simple organic compounds to complex organic compounds? • In the presence of heat, without oxygen, amino acids link to from proteins. • Continue to heat the complex organic compounds protocells developed.
The Evolution of Cells • The first true cells… • Prokaryotes that evolved from a protocell • Anaerobic (no oxygen present in atmosphere) • Autotrophs(photosynthesizing prokaryotes) evolved to inhabit harsh conditions (ie. cyanobacteria) • Cyanobacteriaproduced enough oxygen to support the formation of an ozone layer.
Endosymbiont Theory • Eukaryotes probably evolved from prokaryote cells • Theory proposes that eukaryotes evolved through a symbiotic relationship between prokaryotes • Evidence: • Chloroplast and cyanobacteria – resemble eachother • mitochondria and bacteria – some look similar • Chloroplast and mitochondria contain DNA that is similar to the DNA in prokaryotes • Today, some prokaryotes live in close association with eukaryotes • http://highered.mcgraw-hill.com/sites/9834092339/student_view0/chapter4/animation_-_endosymbiosis.html
Selection Activity *Get into groups of 3’s: 1 recorder, 1 sorter, 1 picker 1. Obtain 2 groups of 1- squares: • Set 1 – 2 red and 8 green • Set 2 – 8 red and 2 green 2. Take set 1. Place the squares numbered side down randomly on the table. Pick a red square and record its number. Replace square. 3. Repeat Step 2 ten times. Clean up set 1. 4. Take set 2. Repeat steps 3 and 4.