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Synthetic Biology Project Examples

Synthetic Biology Project Examples. http://2010.igem.org/Main_Page. Medicine Energy Environment Technology. Medicine. Synthetic Biology Offers New Hope For Malaria Victims March 24, 2004.

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Synthetic Biology Project Examples

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  1. Synthetic Biology Project Examples http://2010.igem.org/Main_Page

  2. Medicine Energy Environment Technology

  3. Medicine

  4. Synthetic Biology Offers New Hope For Malaria VictimsMarch 24, 2004

  5. According to the WHO, each year nearly 500 million people become infected with malaria, and nearly three million — mostly children — die from it.

  6. "By inserting genes from three separate organisms into the E. coli, we're creating a bacterial strain that can produce the artemisinin precursor, amorphadiene. We are now attempting to clone the remaining genes needed for the E. coli to produce artemisinin." -- chemical engineering professor Jay Keasling

  7. Energy

  8. 2008 Project by Harvard iGEM Team http://2008.igem.org/Team:Harvard

  9. Shewanella oneidensis MR-1

  10. Four 2009 iGEM Projects

  11. http://2009.igem.org/Team:HKU-HKBU

  12. http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controllerhttp://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller

  13. http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controllerhttp://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller

  14. http://2009.igem.org/Team:Wash_U http://www.youtube.com/watch?v=mbzObmQKJSo

  15. Environment

  16. Edinburgh iGEM 2006 Awards: Best Real World Application, Best Poster

  17. Poison Water • Arsenic poisoning affects 100 million people • Serious in Bangladesh • Wells tap sedimentary layer with Arsenic • 1 in 4 wells contaminated • Testing methods expensive, require instruments and expertise

  18. Range of Outputs • If no arsenic is present: Urease raises the pH to 9-10 • If 5 ppb arsenic is present: Repressor shuts down Urease, pH remains neutral, pH 7 • If 20 ppb arsenic is present: LacZ produced, pH 4.5

  19. Project Summary Our team have designed and modelled a biosensor that can detect several different concentrations of arsenic and emit a pH signal in response. The device can detect the WHO guideline level of 10 ppb and the Bangladeshi standard of 50 ppb for arsenic in drinking water. A proof of concept Biobrick construct has shown a pH response to a concentration of arsenic of 5 ppb.

  20. Technology

  21. http://parts.mit.edu/igem07/index.php/Peking

  22. Toggle Switch

  23. Toggle Switch NOR Logic Gate

  24. Toggle Switch

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