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venous thromboembolism VTE

? ?. ?VTE???????????? ???? ?????????(Deep vein thrombosis DVT)????(Pulmonary embolism PE)? Eric, K.,

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venous thromboembolism VTE

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    1. ???????? venous thromboembolism (VTE) ???:???

    2. ? ? ?VTE???????????? ???? ?????????(Deep vein thrombosis DVT)????(Pulmonary embolism PE)? Eric, K., & Peter, H.(2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29.

    3. ? ? ??????????20???? ??DVT,???1?2???PE? ??????????50???DVT, ???????DVT??30%??PE? Eric, K., & Peter, H.(2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29.

    4. ??VTE ????? ??? ????? ????????? ??????? ????????????? Eric, K., & Peter, H.(2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29.

    5. ?????????? ?????? ???????? ????????? Eric, K., & Peter, H.(2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29.

    6. VTE????? (Circhoe's Triad) ?????(stasis) ?????(vessel injury) ?????????? (hypercoagulabe state of blood) Eric, K., & Peter, H.(2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29.

    7. DVT???? ??????????? Homan's Sign(+)????

    8. VET?????

    9. Assessing the pretest probability of a first episode of deep venous thrombosis

    10. ??VET???

    11. Clinical approach to the diagnosis of DVT

    12. ?????VET?? ???: ?????(Anticoagulants) ???????(Antiplatalet Therapy ??????(Thrombin Inhibitors )

    13. ????(Anticoagulants) ?Heparin: ?????????,????????????;???????????????,??????????????,??????????(adhensiveness)????????(antithrombin ?)?????(thrombin)??,???????????????(?a)?????

    14. ????(Anticoagulants) ?unfractionated eparin (UFH): ??70?VET???,??Heparin ?????aPTT,????1.5? 2.5??

    15. ????(Anticoagulants) Heparin?????: ?????????????: 5000 U S.C q8h or q12h or adjusted low- dose heparin ?????????: 5000 U IV bolus follow by 24000 U q24h IV infusion or 35000 U?40000 U q24h S.C adjusted to maintain apt in the theraputic range

    16. ????(Anticoagulants) ? Heparin???: ???? ???????effect??: ?urticaria ?thrombocytopenia ?osteoporosis?osteopenia ?alopeciaadr?necrosis

    17. ????(Anticoagulants) ?Low-molecular-eight heparin(LMWH): ????Heparin?1/3,??????????antithrombin ??thrombin??? ?Enoxaparin(Clexane):????????,????????????;?????,????????????? ?UFH ?LMWH???????

    18. ????(Anticoagulants) ?Fondaparinux(Arixtra): ??????????,?????????Xa,??????????????,???????????????? ?Warfarin(Coumadin ): ???????????,????????,???????PT?INR?? ???:????(necrosis)

    19. ??????Antiplatalet Therapy ?Aspirin: ?? cyclo-oxygenase ???,??????????????Aspirin??????cyclo-oxygenase ???,????????????????????????-thromboxane A2????

    20. ?????(Thrombin Inhibitors ) ?Ximelagatran(Exanta ): ??????????(thrombin IIb)???????,??????????????VTE??? ??????????,??: ????????????(????????stroke???????????????????…?)

    21. ?????VET?? ??????: ?graduated compression stockngs(GCS) ?intermittent pneumatic compression(IPC) ?venous foot pumps ?inferior vena cava filters(IVC)

    22. VET???? ???: ?????????????DVT???? ???????????? ???: ??????????????VET??? ?????

    23. ???? Eric, K., &Peter, H. (2007). primary prophylaxis of venous thromboembolism in surgical patient. Hospital Physician, 49(8), 17-29. Motsch, jihann., Walther, Andreas.,Bock, Matthias.,& bottiger, Bernd,W. (2006).Update in the prevention and treatment of deep vein thrombosis and pulmonary embolism. current opinion in Anaesthesiolog, 19(1), 52-58. Pagella, Patrick., Cipolle, Mark., Sacco, Eileen., Mayula, Pat., Karoly, Elizabeth.;& Bokovoy, Joanna. (2007).A Randomized Trial to Evaluate Compliance in Terms of Patient Comfort and Satisfaction of Two Pneumatic Compression Devices.National Association of Orthapedic Nurses Volume, 26(3), 169-174. Deborah, Cook., Maureen, Meade., Gordon, Guyatt., Lauren, Griffith., John, Granton., William, Geerts.; & Mark, rowther.(2004)Clinically important deep vein thrombosis in the intensive care unit:a survey of intensivists.Crit Care, 8(3), 145-152. Wai, Khoon, Ho,. Graeme, J, Hankey,. Vindy, H, Lee.; & John, W, Eikelboom.(2005)Venous thromboembolism: diagnosis and management of deep venous thrombosis.The Medical Journal of Australia, 182(9), 476-481. ???????(2005)·???????????·????,55(4)259-270? ???????(2006)·???????????·????,58(1)28-39? ???????????????????????(2006)·???????????????????·????,58(2)107-111?

    24. ????

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