CHEMISTRY OF HETEROCYCLIC COMPOUNDS

1. Heterocyclic Chemistry CHEMISTRY OF HETEROCYCLIC COMPOUNDS Heterocyclic Chemistry

2. benzene cyclohexane WHAT IS HETEROCYCLIC CHEMISTRY? What are carbocyclic compounds?

3. Carbocyclic Compound

4. What’s aheterocyclic compound? If the ring system is made up of carbon atoms and at least one other element, the compound can be classified as hetero cyclic. The elements that are found most commonly together with carbon in a ring system are Nitrogen (N), Oxygen(O), and Sulfur(S).

5. Heterocyclic Chemistry Heterocyclic compounds are organic compounds that contain a ring structure containing atoms in addition to carbon, such as sulfur, oxygen or nitrogen, as the heteroatom.

6. X X Heteroaromatic Heterocyclic compounds X X Heteroalicyclic Heterocyclic Chemistry Heterocyclic classification It can be classified into

7. Oxirane Piperidine Heterocyclic Chemistry Heterocyclic classification 1- Aliphatic heterocycles :-

8. Pyridine Heterocyclic Chemistry 2- Aromatic heterocycles :- a- six-membered aromatic hetrocycles Pyrimidine

9. Furan Thiophen Heterocyclic Chemistry 2- Aromatic heterocycles :- b- five-membered aromatic hetrocycles

10. Indol Quinoline Heterocyclic Chemistry 2- Aromatic heterocycles :- c- bicyclic heteroaromatic compounds

11. Heterocyclic Chemistry • Importantce and uses of Heterocyclic compounds:- • Biosynthesized • Essential for life ( haem, chlorophyll) • Their metabolitis used as • - toxin towords off predators • - colouring agents to attact mates • In general various important compounds such as:- • alkaloids, vitamins, antibiotics, essential amino acids, hormones, drugs and dyes contain heterocyclic structure.

12. Heterocyclic Chemistry • in general: nucleic acids, amino acids (proteins), • feeding: proteins, carbohydrates, vitamins • alkaloids: nicotine, caffeine Application: • antibiotics (penicillins, sulfonamides) • insecticides (triazoles) • herbicides (triazines, pyridines)

13. Heterocyclic Chemistry 2/3 of all organic compounds are heterocyclic compounds

14. Heterocyclic Chemistry • The main focus:- • * Five-membered systems containing one heteroatom • * Six-membered system containing one heteroatom

15. HETEROCYCLIC NOMENCLAUTURE