Terese Rakow, PhD. Postdoctoral Career Development Course March 10, 2008

1. Terese Rakow, PhD. Postdoctoral Career Development Course March 10, 2008 03/10/2008

2. Highpoints • What is commercialization • What we do • Structure varies with school • Interaction with Technology Transfer Office (TTO) • OR • HOW TO WORK WITH YOUR TTO

3. Inventions to New Products Federal & industry funding

4. Notes on Commercialization • Transfer of research discoveries to the marketplace to benefit patients and the public • Faculty are the source of technology. When something is developed in your lab that may have commercial potential contact your TTO. • If you are unsure contact your TTO

5. Notes on Commercialization • Possible outcomes: • License to large pharma or device co. • License to small biotech or device co. • License to start-up company / venture group Not all technologies get licensed

6. What can be Commercialized • Technology that solves a problem or improves a process: • Cell lines • Clones • Vectors • Research tools • Transgenic or knockout animal models • Diagnostic probes • Therapeutics • Devices • Software • Educational materials

7. When To Contact TTO Contact the TTO BEFORE public use, publication or presentation to help protect against the loss of certain patent rights. Not all discoveries will be patented.

8. What We Do • Evaluate technologies for commercial viability • Market technologies to industry • Arrange for patent prosecution if needed • Negotiate license terms • Draft license agreements • Coordinate legal review and approval of license agreements

9. What We Do (continued) • Receive license income and coordinate distribution • Monitor licensee performance • Report technologies to appropriate sources • Educate about the licensing process

10. Some Things Vary • Some schools: • Triage • Divide work by; technology area, departments, process stage, agreement type • Patent everything or nothing (or so it seems) • TTO is a foundation or a for-profit • VC group or VC fund for start up

11. Some Things Don’t • The Institution owns data, results, inventions, etc. This includes notebooks • The goal is a license NOT a patent. • Licenses take time, patents take longer

12. Relationships • We depend on faculty to communicate new ideas and discoveries • We would rather hear too much, too often; than, too little, too late

13. Relationships • Caution – do not put too much in writing, ask to meet with your TTO • If a company or attorney contacts you about your research contact your TTO • Don’t commit (license / SRA)

14. Relationships • The TTO will need to see data. • If you have information on market, science, etc. provide it • If you have questions, ask

15. Relationships • If commercialization is of interest ask to meet with TTO when interviewing for jobs • Learn more about the process

16. Be Realistic • We do not get points for turning away perfectly good, commercially viable technology • Many things are patentable, but not commercially viable

17. Be Realistic • It is highly unlikely you will get rich • ~1.4% of all licenses generate over $1M in revenue/year

18. Be Realistic • 1 in 10 funded start ups might result in a home run (100’s do not get funded) • 3 in 10 might survive • You need to let it go for it to survive

19. What is in it for Developers • Contribution to healthcare and research • Expand collaborations • Net income is distributed: • developers • department • school operations etc.

20. Other Agreements • Other agreements might be handled by TTO • Confidential Disclosure Agreements • Sponsored Research Agreements • Clinical Trial Agreements • Material Transfer Agreements to academics

21. Contact Information Terese Rakow, Ph.D. Sr. Licensing Associate Baylor Licensing Group Baylor College of Medicine 713 798-6821 phone 713 798-1252 fax www.bcm.edu/blg/ Physical location: BCMD-600D - Jewish Wing trakow@bcm.edu

22. Questions?