Dr. Szucs Attila gy gyszer sz-k zgazd sz int zeti fogy gyszer sz 2009. okt ber 13.

1. Gy�gyszer haszn�lat alapveto k�rd�seiLimf�ma klub Dr. Szucs Attila gy�gyszer�sz-k�zgazd�sz int�zeti fogy�gyszer�sz 2009. okt�ber 13.

2. Defin�ci�k Gy�gyszer Gy�gyterm�k �trend kieg�sz�to Speci�lis t�pszerek

3. Gy�gyszer defin�ci�ja: b�rmely anyag vagy azok kever�ke, amelyet emberi betegs�gek megeloz�s�re vagy kezel�s�re �ll�tanak elo (vagy azok az anyagok vagy kever�kei, amelyek farmakol�giai, immunol�giai vagy metabolikus hat�sok kiv�lt�sa r�v�n) az ember valamely �lettani funkci�j�nak helyre�ll�t�sa, jav�t�sa vagy m�dos�t�sa, illetve az orvosi diagn�zis fel�ll�t�sa �rdek�ben alkalmazhat�.

4. Szigor� vizsg�latok ut�n lehet alkalmazni

5. Gy�gyterm�k EU nem ismeri ezt a kateg�ri�t Gy�gyszerr� vagy �trend kieg�sz�tov� minos�tik �t

6. Az �trend-kieg�sz�tok olyan �lelmiszerek, amelyek a hagyom�nyos �trend kieg�sz�t�s�t szolg�lj�k, �s koncentr�lt form�ban tartalmaznak t�panyagokat vagy egy�b t�pl�lkoz�si vagy �lettani hat�ssal rendelkezo anyagokat, egyenk�nt vagy kombin�ltan. Ellenorz�s??? Csak bejelent�si k�telezetts�g!

7. Felnottek sz�m�ra aj�nlott napi vitamin �s �sv�nyi anyag beviteli referencia �rt�kek (RDA)

11. Speci�lis t�pszerek A k�l�nleges t�pl�lkoz�si c�l� �lelmiszernek ki kell el�g�tenie: az olyan fogyaszt�k speci�lis t�pl�lkoz�si ig�nyeit:- akik em�szt�si vagy anyagcserezavarban szenvednek- akiknek saj�tos �lettani �llapotuk miatt bizonyos anyagok ellenorz�tt m�rt�kben t�rt�no fogyaszt�sa elony�s (Avemare) valamint, az eg�szs�ges csecsemok �s kisgyermekek speci�lis t�pl�lkoz�si ig�nyeit

12. Felsz�v�d�s a sz�j�regbol M�j elker�l�se, gyors hat�s, boml�s elker�l�se Nem szokv�nyos, rossz �z, kis d�zis Pl. angin�s rohamok - nitroglicerin

13. First-pass Effect

14. Felsz�v�d�s a gyomorb�l Bo v�rell�t�s Motilit�s pH B�zikus molekula Sav �s em�sztoenzimek Lass� Csak egy�ttmuk�do beteg M�j metabolizmus

15. Felsz�v�d�s a v�konyb�lbol, vastagb�lbol B�lbolyhok Nagy fel�let rectum (k�pok, klizm�k)

16. Felsz�v�d�s a t�dobol Hatalmas fel�let 100 m2

17. Felsz�v�d�s a bor fel�let�rol Speci�lis tapaszok Legt�bbsz�r helyi hat�s

18. Parenter�lis bevitel Intracutan Subcutan Intramuscularis Intraarteri�lis Itrav�n�s Intrathec�lis Intraperitone�lis Intrapleur�lis Intraarticul�ris intracardi�lis

19. D�zist befoly�sol� t�nyezok �letkor � idosek: metabolizmus, kiv�laszt�s? Feh�rj�k (�hez�s) Tolerancia Genetikai faktorok nem

20. Egy kis technol�gia:Transzderm�lis Tapaszok (TTS= transdermal system) L�z!

21. 24 �r�s hat�s� tablett�k(�szellem tabletta�)

22. Adagol�s

23. Interakci�k - k�lcs�nhat�sok M�dos�tj�k a hat�st Rossz - j� (Gy�gyszer � gy�gyszer) Gy�gyszer - �tel

24. Betegek aggodalma1008 beteg This figure shows data from a national survey conducted in 1999 by the American Society of Health Systems Pharmacists (ASHP) that evaluated patient concerns about health systems. This was a random telephone survey of 1,008 adults. Although the respondents were very concerned about suffering from pain and the cost of filling prescriptions, they were most concerned about being given the wrong drug or that a drug interaction would occur. The public in general has a much greater level of concern about ADRs than most health care providers would suspect. These data demonstrate that drug interactions and reactions are not only a concern to health care providers but to patients as well. American Society of Health Systems Pharmacists. ASHP Patient Concerns National Survey Research Report. 1999. Bethesda, MD. This figure shows data from a national survey conducted in 1999 by the American Society of Health Systems Pharmacists (ASHP) that evaluated patient concerns about health systems. This was a random telephone survey of 1,008 adults. Although the respondents were very concerned about suffering from pain and the cost of filling prescriptions, they were most concerned about being given the wrong drug or that a drug interaction would occur. The public in general has a much greater level of concern about ADRs than most health care providers would suspect. These data demonstrate that drug interactions and reactions are not only a concern to health care providers but to patients as well. American Society of Health Systems Pharmacists. ASHP Patient Concerns National Survey Research Report. 1999. Bethesda, MD.

25. Egy�tt alkalmaz�sa �telnek, italnak gy�gyszernek � k�r�ltekintoen K�rdezze orvos�t Besz�lje meg gy�gyszer�sz�vel Olvassa el a t�j�koztat�t Any time you take a drug you need to learn all you can about that drug and its possible side effects. To get this information, you can Ask your doctor questions as he prescribes it Talk to your pharmacist when you buy the drug (this service is actually required by law so don�t hesitate to ask for it) Read the information about the drug provided by the pharmacy Read the medicine label or manufacturer�s information in the drug package (especially if the drug is not a prescription) Any time you take a drug you need to learn all you can about that drug and its possible side effects. To get this information, you can Ask your doctor questions as he prescribes it Talk to your pharmacist when you buy the drug (this service is actually required by law so don�t hesitate to ask for it) Read the information about the drug provided by the pharmacy Read the medicine label or manufacturer�s information in the drug package (especially if the drug is not a prescription)

26. A feleloss�g az Tied! Mondd el az orvos�nak az �sszes �n �ltal szedett gy�gyszert Vidd el az �sszes m�s orvos �ltal fel�rt javasolt gy�gyszert It is very important that your doctor and pharmacist know all the drugs you are taking. This includes any over the counter drugs like aspirin, vitamin � mineral supplements or herbal supplements. If you see more than one doctor or use more than one pharmacy, you need to be sure all of them know about all your medications. A good practice is to take a bag containing all your medicines and supplements with you to each doctor visit to review them. Doing this will be especially important if you get a new medicine or the doctor wants to change the dose of a medicine you currently use. Give out a lunch size paper bag marked �MEDICINES� with a magic marker to each participant. (These bags can be obtained in most grocery stores)It is very important that your doctor and pharmacist know all the drugs you are taking. This includes any over the counter drugs like aspirin, vitamin � mineral supplements or herbal supplements. If you see more than one doctor or use more than one pharmacy, you need to be sure all of them know about all your medications. A good practice is to take a bag containing all your medicines and supplements with you to each doctor visit to review them. Doing this will be especially important if you get a new medicine or the doctor wants to change the dose of a medicine you currently use. Give out a lunch size paper bag marked �MEDICINES� with a magic marker to each participant. (These bags can be obtained in most grocery stores)

27. �ltal�ban Egy poh�r v�zzel vegye be gy�gyszer�t! One beverage is definitely beneficial when taking medications in pill or capsule form. That is water. Every time you take a pill or capsule, be sure to drink at least 8 ounces of water. Water helps to dissolve the medicine and improve its absorption. Diluting and dissolving some medicines with water also may make them less likely to irritate or upset your stomach. One beverage is definitely beneficial when taking medications in pill or capsule form. That is water. Every time you take a pill or capsule, be sure to drink at least 8 ounces of water. Water helps to dissolve the medicine and improve its absorption. Diluting and dissolving some medicines with water also may make them less likely to irritate or upset your stomach.

28. Grapefruit Okozhat magasabb gy�gyszer koncentr�ci�t � ak�r toxikus szintet is A gy�gyszer hat�stalan lesz A new concern is the effect of grapefruit and grapefruit juice on drugs. Grapefruit can inactivate an enzyme that controls the amount of a medicine that is absorbed from the intestines. For many drugs this increase may result in very high levels of the medicine in the body that may be toxic. Also grapefruit can cause some drugs to not work as well as expected.This is the case for Viagra, the impotence drug and Allegra, a drug used for controlling allergies. These negative affects can continue for 24 hours after drinking or eating the fruit. Since tangelos are a hybrid of grapefruit, you also need to avoid them. Always ask your doctor of pharmacist whether you should avoid grapefruit or grapefruit juice when taking a drug. Unfortunately, some printed literature that you might get about a drug may not specifically tell whether grapefruit affects the drug, so you must ask. A new concern is the effect of grapefruit and grapefruit juice on drugs. Grapefruit can inactivate an enzyme that controls the amount of a medicine that is absorbed from the intestines. For many drugs this increase may result in very high levels of the medicine in the body that may be toxic. Also grapefruit can cause some drugs to not work as well as expected.This is the case for Viagra, the impotence drug and Allegra, a drug used for controlling allergies. These negative affects can continue for 24 hours after drinking or eating the fruit. Since tangelos are a hybrid of grapefruit, you also need to avoid them. Always ask your doctor of pharmacist whether you should avoid grapefruit or grapefruit juice when taking a drug. Unfortunately, some printed literature that you might get about a drug may not specifically tell whether grapefruit affects the drug, so you must ask.

29. tejterm�kek Tetracycline - vas sem! Gombaellenes gy�gyszerek Pl: Diflucan and Nizoral Some drugs do not work when dairy products are consumed. These include tetracycline, an antibiotic and several anti-fungal medicines like Diflucan and Nizoral. Also iron supplements can cause tetracycline to not work well. Some drugs do not work when dairy products are consumed. These include tetracycline, an antibiotic and several anti-fungal medicines like Diflucan and Nizoral. Also iron supplements can cause tetracycline to not work well.

30. �Hieroglif�k� SR � slow release MR - modified XL ZOK � zero order kinetics HA, AR � hypoallergen, antireflux LA � long acting HCT � hydrochlortiazid TDS � trans dermal system EC � b�lben old�d� bevonat

31. V�ny n�lk�l kaphat� szerek orrcsepp Aspirin � gyomorb�ntalom, v�rz�s, asthma, enalapril Paracetamol � 104 f�le ? m�jk�rosod�s Ibuprofen � alkohollal ? gyomor v�rz�s K�h�g�s csillap�t�k Sav k�tok (Al, Mg, Ca � sav termel�st cs�kkentok) sz�dabikarbon�t (Na, sav,) �digoxin, doxiciclin Hashajt� � mennyis�g�t, b�lmozg�st serk, olajok, ozmotikus antiallergia

32. Aktualit�sSert�s influenza ???H1N1 v�doolt�s

33. K�sz�n�m a figyelmet!