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This study explores the correlation between academic research papers and patent filings in the chemical sciences. It examines the impact of research sponsorship, publishing, patenting, licensing, and technology transfer in universities. The interplay between government and industry funding in university research is also investigated.
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Mapping Academic Patents to Papers Hyun-Woo Kim,1 Zhen Lei,1 Brian Wright,2 John Yen1 1 Penn State University 2 UC Berkeley NAS SciSIP PI Conference September 20-21, 2012
NSF SciSIP Project • Collaborative Research: • The Impacts of University Research and Funding Sources in Chemical Sciences: Publishing, Patenting, Commercialization • PIs: Brian Wright (UC Berkeley) and Zhen Lei (Penn State) • Role of research sponsor type (government or industry) on university research, patenting, technology transfer • Publishing, patenting, licensing/ MTAs, and diffusion and follow-on research of university inventions • Interplay between government and industry funding in university research
Datasets • Data 1: • Access to University of California Office of Technology Transfer: • Invention disclosures, patenting and licensing history • Sponsor information, technology information • Data 2: • All scientific publications in chemical sciences by UC researchers in 1975-2005, and the associated citation profile of these publications
Patent/Paper Correspondence:One-to-One in Theory A paper Same researchers Close dates An invention A patent
Not So Clean in Practice Patent filing Patent filing Continuation Grant Papers Papers
Features of a Patent-Paper Pair • Feature Group 1 (paper coauthors’ names): • Does first co-inventor’s last name appear in the co-author list? • Does first co-inventor’s “fist initial and last name” appear in the co-author list? • Does first co-author’s last name appear in the co-inventor list? • Does first co-author’s “fist initial and last name” appear in the co-inventor list? • Does last co-author’s last name appear in the co-inventor list? • Does last co-author’s “fist initial and last name” appear in the co-inventor list? • Fraction of patent inventors whose first initial and last name appear in the coauthor list of the paper • Fraction of patent inventors whose last names appear in the coauthor list of the paper
Features of a Patent-Paper Pair • Feature Group 2 (paper primary affiliation): • String similarity score (Levenshtein Distance) between patent assignee and paper primary affiliation • Percentage of the common words between patent assignee and paper primary affiliation • Is the patent assignees’ country the same as the paper primary affiliation’s? • Is the patent assignee’s (city or state)+country is the same is the paper primary affiliation’s? • Does first co-inventor’s country appear in the paper primary affiliation? • Does first co-inventor’s city/state and country appear in the paper primary affiliation? • Fraction of the inventors whose countries are same as the paper primary affiliation’s • Fraction of the inventors whose city/state and country are same as the paper primary affiliation’s
Features of a Patent-Paper Pair • Feature Group 3 (content similarity): • Fraction of the common words in patent and paper titles • Fraction of the common words in patent and paper abstracts • Fraction of the paper’s chemical substances that appear in patent title • Fraction of the paper’s chemical substances that appear in patent abstract
Features of a Patent-Paper Pair • Feature Group 4 (Timing): • Abs (Paper publication year – Patent filing year) • Abs (Paper publication year – Earliest patent filing year)
Data • Murray/Stern Data • 165 pairs of Nature Biotech paper /US patent • Our Experiment • 165 patents: 162 with one GT (ground truth) paper, 3 with 2 GTs • Retrieve papers from PubMed that share at least one last name • Filtering: • Exclude Review Articles • (Earliest patent filing year -2) TO (Patent filing year +5) • A total of 247322 patent-article pairs • 1498.92 articles/patent on average
Experiment 1 • 10-fold Cross Validation • Algorithms to Build Models Logistic Regression Normal-Identity Regression Binomial-LogLog Regression Binomial-Probit Regression An ensemble method averaging all above
Model Comparison (rank of GT) • Use all features Model Logistic Nor-Identity Bin-LogLog Bin-Probit Ensemble Upper Lower 3.1647 3.5393 3.5276 3.5276 3.0640 3.4449 3.1018 3.4765 2.8788 2.8788
Tagging • Evaluate top ranked papers for each patent to see if they are GTs as well? • 1120 patent-paper pairs have been evaluated and tagged. • Not GTs: 566 pairs • Uncertain: 4 pairs • GTs: 550 pairs
Histograms: (# of GTs per Patent) Before Tagging After Tagging
Experiment 2 • Updated GT papers for each patent • 10-fold Cross Validation • Algorithms to Build Models Logistic Regression Normal-Identity Regression Binomial-LogLog Regression Binomial-Probit Regression An ensemble method averaging all above
Model Comparison(rank of 1st GT) • Use all features Model Logistic Nor-Identity Bin-LogLog Bin-Probit Ensemble Upper Lower 1.0739 1.0739 1.1923 1.1923 1.0680 1.0680 1.0739 1.0739 1.0870 1.0870
Model Comparison (fraction of GTs in Top k) • Use all features
Summary • An algorithm to link patents to papers • Useful tool for studying dynamics and interaction in utilization of university inventions by both academia and industry, and impacts of university patenting and licensing • Useful tool for evaluating impacts of government funding
Fraction of patent inventors whose last names appear in GT papers