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1. Spinal Cord Anatomy AP 150
Chapter 12
3. Meninges Connective tissue membranes
Dura mater: outermost layer; continuous with epineurium of the spinal nerves
Arachnoid mater: thin and wispy
Pia mater: bound tightly to surface
Forms the filum terminale
anchors spinal cord to coccyx
Forms the denticulate ligaments that attach the spinal cord to the dura
Spaces
Epidural: external to the dura
Anesthestics injected here
Fat-fill
Subdural space: serous fluid
Subarachnoid: between pia and arachnoid
Filled with CSF
4. Cross Section of Spinal Cord Anterior median fissure and posterior median sulcus
deep clefts partially separating left and right halves
Gray matter: neuron cell bodies, dendrites, axons
Divided into horns
Posterior (dorsal) horn
Anterior (ventral) horn
Lateral horn
White matter
Myelinated axons
Divided into three columns (funiculi)
Ventral
Dorsal
lateral
Each of these divided into sensory or motor tracts
5. Cross section of Spinal Cord Commissures: connections between left and right halves
Gray with central canal in the center
White
Roots
Spinal nerves arise as rootlets then combine to form dorsal and ventral roots
Dorsal and ventral roots merge laterally and form the spinal nerve
6. Organization of Spinal Cord Gray Matter Recall, it is divided into horns
Dorsal, lateral (only in thoracic region), and ventral
Dorsal half sensory roots and ganglia
Ventral half motor roots
Based on the type of neurons/cell bodies located in each horn, it is specialized further into 4 regions
Somatic sensory (SS) - axons of somatic sensory neurons
Visceral sensory (VS) - neurons of visceral sensory neur.
Visceral motor (VM) - cell bodies of visceral motor neurons
Somatic motor (SM) - cell bodies of somatic motor neurons
7. Gray Matter: Organization
8. White Matter in the Spinal Cord Divided into three funiculi (columns) posterior, lateral, and anterior
Columns contain 3 different types of fibers (Ascend., Descend., Trans.)
Fibers run in three directions
Ascending fibers - compose the sensory tracts
Descending fibers - compose the motor tracts
Commissural (transverse) fibers - connect opposite sides of cord
9. White Matter Fiber Tract Generalizations Pathways decussate (most)
Most consist of a chain of two or three neurons
Most exhibit somatotopy (precise spatial relationships)
All pathways are paired
one on each side of the spinal cord
10. White Matter: Pathway Generalizations
11. Descending (Motor) Pathways Descending tracts deliver motor instructions from the brain to the spinal cord
Divided into two groups
Pyramidal, or corticospinal, tracts
Indirect pathways, essentially all others
Motor pathways involve two neurons
Upper motor neuron (UMN)
Lower motor neuron (LMN)
aka anterior horn motor neuron (also, final common pathway)
12. Pyramidal (Corticospinal) Tracts Originate in the precentral gyrus of brain (aka, primary motor area)
I.e., cell body of the UMN located in precentral gyrus
Pyramidal neuron is the UMN
Its axon forms the corticospinal tract
UMN synapses in the anterior horn with LMN
Some UMN decussate in pyramids = Lateral corticospinal tracts
Others decussate at other levels of s.c. = Anterior corticospinal tracts
LMN (anterior horn motor neurons)
Exits spinal cord via anterior root
Activates skeletal muscles
Regulates fast and fine (skilled) movements
13. Corticospinal tracts
14. Extrapyramidal Motor Tracts Includes all motor pathways not part of the pyramidal system
Upper motor neuron (UMN) originates in nuclei deep in cerebrum (not in cerebral cortex)
UMN does not pass through the pyramids!
LMN is an anterior horn motor neuron
This system includes
Rubrospinal
Vestibulospinal
Reticulospinal
Tectospinal tracts
Regulate:
Axial muscles that maintain balance and posture
Muscles controlling coarse movements of the proximal portions of limbs
Head, neck, and eye movement
15. Extrapyramidal Tract
16. Extrapyramidal (Multineuronal) Pathways Reticulospinal tracts originates at reticular formation of brain; maintain balance
Rubrospinal tracts originate in red nucleus of midbrain; control flexor muscles
Tectospinal tracts - originate in superior colliculi and mediate head and eye movements towards visual targets (flash of light)
17. Main Ascending Pathways The central processes of first-order neurons branch diffusely as they enter the spinal cord and medulla
Some branches take part in spinal cord reflexes
Others synapse with second-order neurons in the cord and medullary nuclei
18. Three Ascending Pathways The nonspecific and specific ascending pathways send impulses to the sensory cortex
These pathways are responsible for discriminative touch (2 pt. discrimination) and conscious proprioception (body position sense).
The spinocerebellar tracts send impulses to the cerebellum and do not contribute to sensory perception
19. Nonspecific Ascending Pathway Include the lateral and anterior spinothalamic tracts
Lateral: transmits impulses concerned with pain and temp. to opposite side of brain
Anterior: transmits impulses concerned with crude touch and pressure to opposite side of brain
1st order neuron: sensory neuron
2nd order neuron: interneurons of dorsal horn; synapse with 3rd order neuron in thalamus
3rd order neuron: carry impulse from thalamus to postcentral gyrus
20. Specific and Posterior Spinocerebellar Tracts