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Suprarenal tumors Role of RT

Suprarenal tumors Role of RT. Mahmoud ElGantiry Professor of Radiation Oncology. Role of Radiotherapy. Rare tumors. Retrospective studies. Small number of patients. Not Radiosensetive tumors. Role of Radiotherapy. ADJUVANT: controversial.

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Suprarenal tumors Role of RT

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  1. Suprarenal tumorsRole of RT Mahmoud ElGantiry Professor of Radiation Oncology

  2. Role of Radiotherapy • Rare tumors. • Retrospective studies. • Small number of patients. • Not Radiosensetive tumors.

  3. Role of Radiotherapy ADJUVANT: • controversial. • ?? adjuvant treatment after complete resection for residual microscopic disease. • A 10-year crude survival rate of 37% has been reported after combined surgery and irradiation for functioning adrenal carcinomas. • However, in these tumors an earlier stage at diagnosis gives a better chance of complete removal.

  4. Role of Radiotherapy POSTOPERATIVE RT: • ?? Treatment of residual macroscopic disease and nodal. • Long-term objective tumor control.

  5. Role of Radiotherapy PALLIATION: • Inoperable: • Distant metastases e.g. Bone metastases. • Good response.

  6. Thank you

  7. Staging for tumors of the adrenal gland

  8. CT scan of abdomen illustrating large adrenal glands.

  9. Diagnostic workup for adrenal tumors

  10. Classification of adrenal tumors

  11. General Management Surgery • The primary treatment for adrenocortical carcinoma. • Curative surgery is feasible in only a few patients because of the size of tumor at the time of diagnosis. • However, complete resection is the only treatment that offers long-term disease-free survival. • Surgery can be used as a palliative procedure in patients with incurable functional tumors; partial resections are attempted to improve endocrine manifestations that cannot be controlled medically and to relieve local symptoms. • Careful attention must be given to preoperative, intraoperative, and postoperative steroid replacement, because the contralateral adrenal gland is often atrophied.

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