Molecular Imaging Campaign for Clinical Practice and Drug Development

1. Campaign Overview • To support the translation of molecular imaging research into clinical practice • To foster the use of molecular imaging in drug discovery and development • To engage industry and the molecular imaging community • To raise $5,000,000 over 5 years

2. Value of the Campaign • Recognizes expanding role of molecular imaging in patient care • Builds on SNM’s unique role in medical community • Highlights importance of molecular imaging in drug discovery and development • Ensures imaging practitioners are well prepared to adopt and use this technology • Ensures medical community is well informed and partnerships are formed outside imaging field

3. Goals of the Molecular Imaging Campaign • Provide indispensable resources for education, knowledge exchange, training and networking • Advocate for molecular imaging and therapy • Educate and promote collaboration with referring physicians and patient groups • Support innovations in translational research • Position molecular medicine as an essential tool in providing the highest standards of patient care around the world

4. Provide indispensable resources for education, knowledge exchange, training and networking • Be a central repository for molecular imaging • Create and award grants and fellowships • Develop fellowship and residency curriculum • Conduct workshops to attract and meet diversified needs of molecular imaging practitioners • Implement continuing educational programs and web-based training

5. Provide indispensable resources for education, knowledge exchange, training and networking • Support clinical trials in nuclear medicine and molecular imaging • Implement communications plan to raise awareness that SNM is the indispensable resource for molecular imaging

6. Advocate for molecular imaging and therapy • Proactively lobby for reimbursement and research funding • Strengthen relationships with federal agencies and Congress • Educate community on benefits of molecular imaging and emerging technologies

7. Educate and promote collaboration with referring physicians and patient groups • Create outreach program for referring physicians, patient groups, federal agencies, regulators and the general public

8. Support innovations in translational research • Define translational research from bench to bedside – research to practice • Provide institutional grants for training workshops on translating basic research into clinical application • Develop research programs to assist new investigators in the field of molecular imaging • Identify new funding opportunities

9. Support innovations in translational research (cont’d) • Develop standardized imaging protocols and outcome measures • Define the role of biomarkers in clinical trials • Investigate the implications of molecular imaging in diagnosis and the prediction and monitoring of treatment response • Develop technology assessment mechanism

10. Support innovations in translational research (cont’d) • Assure the viability of MI through the development of techniques that meet a clinical need and that are reimbursable • Partner with basic science organizations, academia, and industry to promote translational research • Position SNM as a central repository for molecular imaging research • Identify and validate new tracers

11. SNM will be recognized as the society that positions molecular medicine as an essential tool in providing the highest standards of patient care around the world • Develop major media marketing plan to influence the introduction and acceptance of molecular imaging technology and benefits • Develop an integrated strategic marketing plan to position SNM as the recognized leader • Increase membership by molecular imaging professionals outside of nuclear medicine

12. Strategic Plan Implementation • Molecular Imaging Center of Excellence has the lead • Developed 9 Task Forces and Editorial Board to implement objectives/strategies for each goal • Task Forces include members of the Center, SNM Committees and Council, and other leaders in the field

13. Overall First Year Accomplishments • Infrastructure and capacity building • Rebranding • New staffing • Governance (elections, nominating committee) • Involvement of SNM and wider MI community • Developed definition for molecular imaging

14. Molecular Imaging Definition Molecular imaging is the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems. • Molecular imaging typically includes two- or three- dimensional imaging as well as quantification over time. • The techniques used include radiotracer imaging/nuclear medicine, MRI, MRS, optical imaging, ultrasound and others.

15. Communications - Highlights • Developed new SNM & MI community Web site • Expanded JNM and Newsline coverage • Created “Road Show,” Newsletter, email blasts with references • Launched media campaign, rebranding • Free trial membership

16. Communications – Looking Ahead • MI Supplement • Begin regular article series in JNMT • Complete brochures on practical benefits • Continue and intensify media campaign • Develop “rapid-action” unit to respond to timely issues through op-eds, etc • New news services, email blasts and web content

17. Advocacy- Highlights • Launched first Capitol Hill Day and MI Week • NCCR Briefing • Held key Federal agency meetings (CMS, NIH, FDA, DOE, OSTP) • Met with key associations, research organizations and companies • Created outreach database • Identifying new research funding sources

18. Advocacy- Looking Ahead • Strengthen strategic partnerships • ASTRO, ASCO meeting collaboration • American Chemical Society, American Academy of Neurology, NIH Cardiovascular Imaging Symposium • Conduct educational forums with coalitions and patient groups • Increase outreach to pharmaceutical companies • Work with NIH Advisory Councils to become official liaison

19. Education – Highlights • Expanded MI focus at MWM, Annual Meeting, in JNM • Molecular Imaging Gateway • Molecular Imaging Supplement • New series of articles • Recommended new clinical/research grants,awards • Developed curriculum for residents • Created speakers’ bureau • Planning for more workshops, training, Summits

20. Education – Looking Ahead • Have new MI Track at Annual Meeting • Hold Second Industry/Expert Summit in February • Develop training workshops and on-line tools • Outreach to residency program directors • Make speaker’s bureau fully operational • Develop “MI scientist” curriculum guidelines • Create scientific “roadshow” for chapters, others

21. Translational Activities – Highlights • Held action planning retreat for imminently emerging technologies in June • Recommendations from retreat to be published in white paper

22. Translational Activities – Looking Ahead • Continuing series of retreats to discuss key issues • New tracer development • Technology assessment and advancement • Translational research education • Standardized imaging protocols • Protocol and regulatory development • Ongoing discussions with FDA

23. MI Center of Excellence Leadership • Martin Pomper, MD., PhD. – President • Henry Van Brocklin, PhD – Vice-President • Carolyn Anderson, PhD – Secretary/Treasurer Staff • Marybeth Howlett, MEM – Staff Director • Communications/Web Site Editor - TBD • Zachary Hochstetler – Program Manager

24. Task Force Chairs • Communications – Al Sinusas, MD • Education – Carolyn Anderson, Ph.D • Advocacy – Robert Atcher, Ph.D • Grants & Awards – Mathew Thakur, Ph.D

25. Task Force Chairs (cont’d) • Definitions – David Mankoff, MD • Emerging Technologies – Sandy McEwan, MD • Future Tracers– Henry VanBrocklin, PhD • Membership – Scott Holbrook, MS CNMT NCT

26. How to Support the Campaign • Corporate donations and pledges • Individual gifts and pledges • Collaboration in task forces, summits • Feedback and ideas • Involvement through MI COE, Web site, list serve

27. Financial Support • Corporate pledges over five years or less • Individual gifts and pledges – Education and Research Foundation • Donor recognition began in 2006

28. Campaign Leadership and Staff • Co-chairs of the campaign: • Hadi Moufarrej, GE Healthcare • Peter S. Conti, M.D., Ph.D.; SNM Past President • Michael D. Devous, Sr., Ph.D.; ERF Past President • SNM Campaign staff: • Virginia Pappas; CEO • Theresa Pinkham, Development Director • Marybeth Howlett; Director, MI Center of Excellence

29. Industry Donor Categories • Corporate Circle: $500,000 or more • Corporate Visionary: $250,000 - $499,999 • Corporate Partner: $100,000 - $249,999 • Corporate Friend: $50,000 - $99,999 • Corporate Contributor: <$50,000