WiSys: Development of Strategic Partnerships to Grow the Economy through Technology Innovation

1. WiSys: Development of Strategic Partnerships to Grow the Economy through Technology Innovation UW System Integrated Marketing and Communication Conference May 31 and June 1, 2012 WiSys Technology Foundation Maliyakal John

2. UW System Outcome From Job Seekers to Job Creators

3. Technology Transfer and Undergraduate Research Economic Opportunity? Pipe Dream?

4. WiSys at a Glance • Affiliate of WARF • Dedicated as the technology transfer office for 11 UW comprehensive campuses and 13 UW colleges • Services began in 2005 • 5 member team • ~110,000 students (60%) • ~3,500 faculty Patent protect discoveries and transfer them to private industry to benefit the UW

5. WiSys Technology Foundation WiSys 4-yr WiSys 2-yr WARF UWMRF

6. UW System • 26 campuses (13+13) • 2 research campuses • 182,000 students • 6,500 faculty members • $4.1 billion budget • 350-450 invention disclosures per year • 3 technology transfer offices 11 Comprehensives ~ 90, 000 students and 3,200 faculty ~$750K in R&D budget ~25-30 invention disclosures

7. WiSys’ Roles • Assist faculty and students to engage in research • Technology assessment • Funding • Collaborations • Technology transfer • Protect discoveries • Transfer technologies to private sector • Share revenue with inventor and campus Develop a Long-Term IP Pipeline

8. WiSys Challenge • No new additional resources • R&D culture missing • Lack of marketable product ideas • Full-time teaching faculty • Multiple, wide-ranging locations How can we build a long-term IP pipeline and contribute to economic growth, scholarship and job creation in Wisconsin?

9. What We Have • 300-400 faculty with technical expertise • Engineering • Material sciences • Chemistry • Computer sciences • High-tech small companies with product concepts • Progressive clinical institutions with medical innovation ideas UW System Resource State Resource

10. Strategy: Build Strategic Partnerships Build a sustainable technology transfer program with minimal new resources • Product ideas • Student internships • Clients • Marketing • Healthcare challenges • Student internships • Clinical resources Partnerships Partnerships Partnerships • Funds • Public relations

11. Strategy • Facilitate the formation of Emerging Technology Centers to tap into the special expertise of faculty and prioritize resources for campuses • Build partnerships with the state’s high-tech small companies to develop products • Build partnerships with progressive healthcare/clinical organizations to develop innovative medical products

12. Strategy • Wisconsin Small Company Advancement Program • Marketable product ideas • Connects with local/regional companies • Student engagement WiSCAP • Advancing innovations • Scholarship • Entrepreneurship • Economic growth Emerging Technology Centers to tap into UW Faculty expertise • Wisconsin Medical Entrepreneurship Foundation • Medical innovation ideas • Clinical resources • Faculty and student engagement WisMEF

13. Emerging Technology Research Centers • Objectives: • Innovative R&D leading to marketable products • Student internships as preparation for high-paying jobs • Entrepreneurship training and startups Scholarship Focus and prioritize Economic Growth Jobs Collaborations

14. Emerging Technology Centers UW-Stout Discovery Center UW-River Falls Tissue and Cellular Innovation Center July, 2009 Mar, 2009 UW-La Crosse Medical Innovation Center UW-Stevens Point Wisconsin Institute for Sustainable Technology Mar, 2011 Sept, 2010 UW-Platteville Nanotechnology Center for Collaborative R&D Dec, 2008 Emerging Technology Research Centers Promote Specialized Research Expertise

15. Wisconsin Small Company Advancement Program (WiSCAP) Joint R&D to develop products for small companies to drive Wisconsin business growth Faculty with technical expertise and resources Companies with product Ideas, but lack of technical expertise Revenue sharing License Product/IP WiSys obtained $2 million in state funding for WiSCAP in 2010

16. WiSCAP Summary • 21 projects initiated involving 17 companies and 9 campuses • ~$2 million allocated to projects • 12,083 hours of student internships • 32 months of release time for 24 faculty members • 16 high-paying jobs • 10 WiSCAP projects advanced to prototypes and lab testing • 1 Option License signed • 3 Option Licenses under negotiation

17. Distribution of WiSCAP Projects

18. WiSCAP: Mercury Removal From Fish Tissue • $2.5 billion WI industry • 30,000 employed • 1.4 million licensed anglers • 400,000 out-of-state anglers per year • Up to 80% mercury removed; flavor improved • Suitable for human and animal consumption • Market introduction in 2012

19. WiSCAP: Supercapacitors for the Energy Industry • Nanomaterial-based technology • Increases energy density by ~20 fold • Field testing with Columbia ParCar A $100 million opportunity

20. WiSCAP: Value Added Products from Cranberry • Antiviral therapeutics • Animal feed supplements • Nutraceuticals 3 compounds with antiviral properties isolated. Characterization and animal studies underway.

21. WiSCAP: Economic Impact of the Wheelchair Project Advanced prototypes being built and human testing planned

22. Pressure Balanced Hydrogen Fuel Cell • Novel design • Low cost • No computer monitoring • Injection molding • Cell staking Prototypes to be installed at Columbia ParCar and Marquis Yachts for field testing

23. Advancing Medical Innovation through Partnerships Technical Expertise Needed for Medical Technology Development • Marshfield, Aurora, BayCareClinics • Knowledge of patient care needs & opportunities • Clinical testing and trials • 3 million patient visits • 3,000 medical professionals • UW, Private industry • Computer-aided design • Electrical, mechanical • Computer, chemistry • Prototyping • ~400 faculty • 90,000 students • Technology transfer WisMEF Marketable Medical Technologies

24. Wisconsin Medical Entrepreneurship Foundation (WisMEF) Private Companies Trade, State Organizations • BioForward • WEDC • Morgridge Institute • EIGER Lab • Gateway College • Kenosha Area Business Alliance (KABA) • Quadripartite • State of Ingenuity Aurora Health Care Marshfield Clinic • AquaCare H20 • Botanic Oil Innovation • Fused Innovation • McDel Topology • mZeal • NovaScan • Perceptral • Procubed • VibeTech WisMEF WisMEF BayCare Clinic WiSys • UW-Eau Claire • UW-Green Bay • UW-La Crosse • UW-Oshkosh • UW-Parkside • UW Extension • - UW-Platteville • UW-River Falls • UW-Stevens Point • UW-Stout • UW-Superior • UW-Whitewater - UW Colleges

25. Potential WisMEF Products Digital Tools/ Hospital Management Polymers/ Composites Scholarship Therapeutics Clinics Company UW Digital Tools/ Rehabilitation Medical Devices Student Internships Digital Tools/ Patient Care Sanitization Products Diagnostics

26. WisMEF: Low-cost 3D Catheter Location Using 2D Fluoroscopy for Cardiac Rhythm Management Aurora Health Care Animal studies Clinical testing Funding • APN LLC • Tech development • Software • Business development • Funding WiSys/UWSP 3D imaging Software Funding IP WEDC Funding Marketing

27. Warfarin: Designing a Safer Anticoagulant Collaboration of UW and Marshfield Clinic • Redesigned 1st generation compounds based on pharmacogenomic studies • Shown efficacy in small animal studies • 2nd generation compounds being synthesized

28. Patient Assist Devices: UW & BayCare Clinic Collaboration • Physician-bioengineer designed • Built by engineering students • Patient tested

29. WisMEF Summary • ~35 product ideas compiled • $1 million in seed funds secured • $1 million in state match funds being considered • ~ 4 projects initiated • Early prototypes built and tested • Bioengineer recruitment in process

30. Impact of WiSys Comprehensives

31. Impact of WiSys

32. Startups: Exceeding Expectations! Prentice Technologies LLC, 2012 Digital tools McDel-Topology LLC, 2011 Pharmaceutical products Tomorrow River Biotechnologies, 2011 Bioenergy Shamrock Energy Corporation, 2010 Supercapacitors Mycophyte Discovery LLC, 2006 Antimicrobial therapeutics CoreTxt Plus LLC, 2011 E-Books NovaScan LLC, 2004 Medical imaging Xolve LLC, 2008 Nanomaterials Foundry Solutions LLC, 2012 Investment casting materials Microionic Systems LLC, 2011 Carbon products

33. Strong Entrepreneurship in UW Comprehensives

34. WiSys will Impact Wisconsin’s Future in an Unprecedented Way • Biodegradable plastics • Nanomaterials • Foundry materials Industrial Materials • Hydrogen fuel cell • Solar energy • Cellulosic energy • Supercapacitors • Biodiesel Digital technologies Patient assist devices Cancer detection Surgical devices Therapeutics Safer food Antimicrobials Nutraceuticals UW Renewable Energy Healthcare Sector

35. Achievements • Developed and implemented a coherent strategy to advance innovation and entrepreneurship in undergraduate institutions • Led formation of 5 Emerging Technology Centers to focus on cutting edge technology development • Formulated and implemented an initiative to partner with high-tech small companies and advance product development • Led the formation of a university-medical institutions-industry network to advance medical innovations and business growth • Advanced entrepreneurship, resulting in the formation of 9 startup companies

36. Work in Progress Engaging undergraduate institutions in R&D can have a significant economic impact for Wisconsin and the country