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Why do Q.A.?

Why do Q.A.?. Physician’s Expectations Diagnosis Therapy Technology. Physician’s Expectations. Diagnosis. Specificity – True Positive in Disease Sensitivity – True Negative. Therapy. Adjustment of Medication. Technology. Complex Instruments Complex Reagents Micro Techniques.

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Why do Q.A.?

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  1. Why do Q.A.? • Physician’s Expectations • Diagnosis • Therapy • Technology

  2. Physician’s Expectations

  3. Diagnosis • Specificity –True Positive in Disease • Sensitivity –True Negative

  4. Therapy • Adjustment of Medication

  5. Technology • Complex Instruments • Complex Reagents • Micro Techniques

  6. What is Q.A.? • Samples • Control Material • Assay Conditionsa. Reagentsb. Instruments • Daily Review • Retrospective Peer Review

  7. Controls • Similar to patient samples • Respond like samples • Stability like samples

  8. Daily Review • Decision Rules • Random Error • Systematic Error

  9. Calculations

  10. Gaussian Distribution

  11. Abnormal Distribution

  12. Graphing – Levey-Jennings Charts

  13. Normal

  14. Westgard Rules 1 – 3s 2 – 2s R – 4s 4 – 1s 10x

  15. 1 – 3s

  16. 2 – 2s

  17. 2 – 2s

  18. R – 4s

  19. 4 – 1s

  20. 10x

  21. Retrospective Peer Review • Measurement of Peer Precision • Method Comparisons • Proficiency Surveys and Routine Q.C.

  22. SDI-Standard Deviation Index

  23. SDI Interpretation • Like Signs • Spread of 1 SDI • Reproducibility

  24. SDI

  25. E = mc 2 Excellence = Methods x Controls x Calculations

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