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Childhood Headache. Rachel Howells. Learning Outcomes. By the end of this session, you should be able to Differentiate primary from secondary headache Recognise and manage common primary headaches. Epidemiology. Preschool 1/3 will have had a headache Migraine headache 0-7% of population
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Childhood Headache Rachel Howells
Learning Outcomes By the end of this session, you should be able to • Differentiate primary from secondary headache • Recognise and manage common primary headaches
Epidemiology Preschool 1/3 will have had a headache Migraine headache 0-7% of population Schoolchildren 70% have ≥ 1 headache a year Peak at 90% at age 12-13 Prevalence of recurrent headache 20-30%
Case 1 15 year old girl • Frontal headache, down neck and shoulders • 2 months • Start as soon as she rises from bed, and relieved by lying down • Missing school for 6 weeks
Case 1 Further history • Spinal surgery 3 months ago • Epidural anaesthesia Examination • Normal
Low pressure headache Possible dural tap Management • Encourage mobilising • Many spontaneously resolve within 3-4 months • Short-term: Caffeine • Long-term: Epidural blood patch
Primary vs Secondary Headache • 10% of headaches seen in a specialist neurology / headache clinic are secondary in origin • Population prevalence of organic disease is likely to be lower
Secondary Headache Types Altered Intracranial Pressure Raised ICP Low Pressure Headaches Vascular Subarachnoid Headache (eg AVM) Dissection Vasculitis Drugs Drug effect Analgesia induced headache Central (thalamic) pain Trigeminal neuralgia Cluster headaches Local Dental Abscess Sinusitis Post head injury
How to identify a secondary headache History Examination Brain Imaging
Indications that a headache is secondary to altered intracranial pressure
Indications • Timing of headache • Postural manoeuvres • Associated symptoms
Morning but from sleep, before rising Morning but after getting up Raised Intracranial Pressure Low Pressure Headache Timing of Headache
Getting up relieves headache Coughing and straining exacerbates it Lying down relieves headache Low Pressure Headache or Sinusitis Raised Intracranial Pressure Postural Manoeuvres
Frontal headache Associations Morning vomiting Other neurology Confusion Frontal headache Associations Pain / parasthesiae across shoulders* Blocked nose, facial pain¤ Raised Intracranial Pressure Low Pressure Headache* or Sinusitis¤ Associated Symptoms
Case 2 16 year old girl seen in OPD • Frontal headache • There when she wakes, gets better when she gets up • No nausea or other neurological symptoms 4 months, not getting any worse
Primary or Secondary? Is this raised or low intracranial pressure?
Case 2 continued Past History – nil Examination • Enlarged blind spots on confrontation • No other alteration of visual fields • Papilloedema • No ataxia, long tract signs
Causes of Raised Intracranial Pressure Hydrocephalus Tumour obstructing CSF pathways Obstruction to CSF re-absorption (post haemorrhage or meningitis) Congenital (eg aqueduct stenosis) Idiopathic (Benign) Intracranial Hypertension Cerebral oedema Inflammation (ADEM, stroke) Infection (meningitis etc) CO2 retention (obstructive sleep apnoea) Metabolic (DKA, other)
Idiopathic Intracranial Hypertension Aetiology unknown • Adolescent girls • Obesity, drugs, steroid withdrawal • Visual loss (10%) may be permanent and is only indication for treatment Raised intracranial pressure in the absence of space occupying lesion or obstruction to CSF flow
Indications • Timing of headache • Postural manoeuvres • Associated symptoms
Case 3 14 year old girl • Headache since the evening before • Single and worst headache ever • Sudden onset Vomited once at start No history of head injury / prodrome
Case 3 Examination • Afebrile • No meningism • GCS 15 • Unilateral facial weakness with frontal sparing • Ipsilateral arm weakness with hyporeflexia
Case 3 CT shows haemorrhage around area of left basal ganglia Patient admits to using some cocaine at a party with her 18 year-old sister
More information to help you identify secondary headache History
Timecourse Migraine? Single or first severe headache Recurrent severe headaches One a month 2 years without progression Bleed? Headaches all day on most days 18 months Headaches every few months then weeks then days Now every day TTH? Tumour? Severe headaches all day for 12 days 2 months ago None since Bleed?
Timecourse Single or first severe headache Recurrent severe headaches One a month 2 years without progression Headaches all day on most days 18 months Headaches every few months then weeks then days Now every day Severe headaches all day for 12 days 2 months ago None since
Pointers in History: Summary • Timing of Headache • Postural manoeuvres • Symptoms associated with headache • Timecourse
Purpose of Examination • To support your clinical impression made on history • To rule out other differentials • To adhere to many families expectations • to be taken seriously • to be able to support your view that nothing serious is going on
Essential elements of Examination Conscious level Vision Acuity Fields including blind spot Extraocular movements Long tract signs Tone Power Reflexes Cerebellar signs Finger-nose test (eyes shut) Tremor Dysarthria Gait Blood pressure Fundi Bruit
Case 4 8 year old boy with 10 month history of • Bi-temporal headache • Throbbing • Worse with movement / exercise • Mother says looks pale and unwell • Usually start in morning • Last all day
Case 4 No family history Examination is normal
Primary or Secondary? What is the most likely diagnosis?
Migraine headache Nerve efferents – trigeminal, vagal Meninges have pain fibres with inputs from trigeminal complex Vasodilation of meningeal vessels What causes migraine? Why do some people get migraine headaches? • Genetic • Abnormal inhibitory inputs to trigeminal nerve complex Michael Creighton
Clinical Implications Abnormal inhibition to nociceptive parts of brain • Abnormal response to changes in environment eg sleep, diet, smells • Pain is exacerbated by noise and light • Headache relieved by sleep in a dark room Migraine symptoms • Pain involves the face (trigeminal) • Throbbing pain (meningeal) • Pallor and nausea (vagal) Delia Malchert
Migraine Classification • Migraine without aura (commonest) • Migraine with aura • Basilar migraine • Ophthalmoplegic migraine • Alternating hemiplegia
Migraine The diagnosis is a clinical one Families can be reassured by • Family history • Longevity of symptoms • Normal examination • Addressing their underlying concerns
Management • Explanation • This is not a tumour • Worst in second decade of life • Most patients will get fewer headaches as they get older
Management 2. Treatment of attacks • Analgesia as soon as an attack starts • Ibuprofen works best (one RCT) • May be supplemented by anti-emetic • Patients over 12 may respond to im, oral or nasal sanomigran (Imigran)