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Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects. Osteoscoop - Issue N°182 - May 2011. Wnt. Enhanced osteoblast differentiation. Frizzled. - catenin. PTH. PTH-R. sFRP 1. Wnt.
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Overexpression of secretedfrizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects Osteoscoop - Issue N°182 - May 2011
Wnt Enhanced osteoblast differentiation Frizzled -catenin PTH PTH-R
sFRP 1 Wnt Enhanced osteoblast differentiation Frizzled -catenin PTH PTH-R
sFRP 1 Wnt Enhanced osteoblast differentiation Frizzled X -catenin PTH Osteopenia PTH-R
sFRP 1 Wnt Enhanced osteoblast differentiation + Frizzled X -catenin PTH Osteopenia PTH-R
sFRP 1 Wnt Enhanced osteoblast differentiation + Frizzled X X -catenin PTH Osteopenia PTH-R