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Mohammad Peikari Advisor: Dr. Gabor Fichtinger

Characterization of Ultrasound Elevation Beamwidth Artefacts for Brachytherapy Needle Insertion. Mohammad Peikari Advisor: Dr. Gabor Fichtinger. Laboratory for Percutaneous Surgery School of Computing, Queen’s University, Canada. Motivation. Gall Bladder

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Mohammad Peikari Advisor: Dr. Gabor Fichtinger

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  1. Characterization of Ultrasound Elevation BeamwidthArtefacts for Brachytherapy Needle Insertion Mohammad Peikari Advisor: Dr. Gabor Fichtinger Laboratory for Percutaneous SurgerySchool of Computing, Queen’s University, Canada

  2. Motivation Gall Bladder (arrow points to false artifact) • All US-guided procedure suffers from section thickness artifacts • Appearance of anatomy and localization of surgical tools affected • Motivating application is the transrectal ultrasound (TRUS) guided prostate brachytherapy Figure: http://www.gehealthcare.com/caen

  3. Achievements • Nominated for best master research award – IEEE Kingston section 2011 • Journal of Medical Physics 2012 (ISI impact factor = 3.25) • Medical Image Computing and Computer Assisted Intervention (MICCAI) conference 2011 (peer reviewed conference proceedings) • International Society for Optics and Photonics (SPIE) 2011 (nominated for best student paper award) • Patented a variation of the presented device by other members of the group

  4. Prostate Cancer • Second leading cause of cancer related death • Treatment options: • Prostatectomy • external beam radiation • Brachytherapy • Potential advantages of brachytherapy: • Outpatient treatment • Comparable to the other treatment options • Ability to target tumor and avoid healthy tissues • Potential disadvantages of brachytherapy: • Side effects may vary • Highest quality is hard to achieve

  5. Prostate Brachytherapy • Permanent implantation of radioactive seeds under live ultrasound (US) guidance Figure credited to C. Chao from Perk lab

  6. Ultrasound www.en.wikibooks.org and http://www.frca.co.uk

  7. Treatment Planning 100% isodose Margin: 3-6 mm www.oncoprof.net

  8. Ultrasound Guided Needle Insertion 1-Postate with target implant location 2-Needle insertion 3-Needle reaches the target http://www.eecs.berkeley.edu

  9. Treatment Validation and Plan Update E. Dehghan et al. “Prostate Implant Reconstruction from C-arm Images with Motion-Compensated Tomosynthesis”,Medical Physics, Vol. 38(10), pp. 5290 – 5302, 2011.

  10. Procedure http://www.prostatebrachytherapyinfo.net/PCT21.html

  11. Section Thickness Artifacts in TRUS • a) Main beam thickness • b) Side lobe energies Main lobe Side lobe

  12. Objectives • Characterization the ultrasound elevation beamwidth • Generate US beam profile • Compare main beam thickness and side lobe artifacts • Measure needle tip localization offsets • Recommendations to reduce the effects of these artifacts

  13. Prior Work on Beamwidth Artifacts • Goldstein (Ultrasound,1981) • Skolnick (Radiology, 1991) • Compared scan plane and section-thicknesses • Used an inclined surface and a phantom with multiple filaments 1cm apart in a vertical row • Difference compared to proposed method: Needs segmentation of the filaments • Richard (Radiology,1999 ) • Used several inclined surfaces located successively below each other in a phantom • Difference compared to proposed method: more complex phantom, results only at specific positions

  14. Prior Work on Side Lobe Artifacts • Laing (Radiology, 1982) • Illustrated the genesis of side lobe artifacts • Employed round plastic container filled with de-gassed water and a sponge • Compared the effects of main and side lobe artifacts • Barthez (Radiology and Ultrasound, 1997) • Reproduced the artifacts using metallic wires and wooden tongue depressor • Employed all sorts of US transducer • Shape and intensity varied with US transducer type

  15. Beamwidth Measurement 45⁰ 45⁰ Beamwidth Main beam thickness Main and side lobe beams thickness • CD≈Ultrasound beamwith • The US beamwidth is larger when side lobe energies present around the main lobe

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