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SPINAL CORD: EXTERNAL FEATURES & BLOOD SUPPLY. Dr. Ahmed Fathalla Ibrahim. NERVOUS SYSTEM. STRUCTURAL CLASSIFICATION: CENTRAL NERVOUS SYSTEM (CNS): Brain , spinal cord PERIPHERAL NERVOUS SYSTEM (PNS): Cranial nerves (carry impulses to & from the brain) + related ganglia
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SPINAL CORD: EXTERNAL FEATURES & BLOOD SUPPLY Dr. Ahmed Fathalla Ibrahim
NERVOUS SYSTEM • STRUCTURAL CLASSIFICATION: • CENTRAL NERVOUS SYSTEM (CNS): Brain, spinal cord • PERIPHERAL NERVOUS SYSTEM (PNS): • Cranial nerves (carry impulses to & from the brain) + related ganglia • Spinal nerves (carry impulses to & from spinal cord) + related ganglia
FUNCTIONAL CLASSIFICATION OF PNS • Sensory (afferent) division:consists of nerves that conduct impulses to CNS • Motor (efferent) division:consists of nerves that conduct impulses from CNS. It is divided into: • Somatic nervous system:concerned with voluntary control of skeletal muscles • Autonomic nervous system:concerned with involuntary control of glands, smooth & cardiac muscles
STRUCTURE & FUNCTION OF NERVOUS TISSUE • THE NERVOUS TISSUE IS FORMED OF TWO TYPES OF CELLS: • NEURONES • NEUROGLIA
NEURONES • Function: conduct nerve impulses • Structure: formed of • Body: contains nucleus • Processes: axon (a single process that conducts impulses away from the cell body) & dendrites (one or more processes that conduct impulses to the cell body)
NEURONES • Coverings: • Myelin sheath:fatty sheath, present in both CNS & PNS, formed by: neurilemma (in PNS) & neuroglia (in CNS), function: insulates neurones • Neurilemma (Schwann cells):cellular sheath, present in PNS only, function: regenerates axons & forms myelin
CLASSIFICATIONS OF NEURONES • According to number of processes: • Unipolar neurons • Bipolar neurons • Multipolar neurons • According to function: • Sensory (afferent) neurones: carry impulses from receptors to CNS • Motor (efferent) neurones : carry impulses from CNS to muscles & glands • Interneurones: connect sensory & motor neurones
NEUROGLIA • Function: support, protect & insulate neurons • Difference between neuroglia & neurones: • Neuroglia do not transmit nerve impulses • Neuroglia never lose the ability to divide
DEFINITIONS • NUCLEUS:Collections of cell bodies of neurones having the same function found in CNS • GANGLIA:Collections of cell bodies of neurones having the same function outside CNS • TRACT:collection ofaxons of neurones having the same origin, termination & function found in CNS • NERVES:collection ofaxons of neurones having the same origin, termination & function outside CNS • GREY MATTER OF A PART OF CNS:collections of all nuclei in that part of CNS • WHITE MATTER OF A PART OF CNS:collections of all tracts in that part of CNS
PROTECTION OF CNS • BONE: Skull, vertebral column • MENINGES: 3 fibrous membranes that covers the CNS: • Dura matter: outer, tough • Arachnoid matter: middle, web-like • Pia matter: inner delicate, vascular • CEREBROSPINAL FLUID: • Fluid similar to plasma in composition • Formed from blood in the capillaries present inside cavities of CNS (Choroid plexus) • Circulates in cavities of CNS then around CNS (between arachnoid & pia matter) • Forms a water jacket around CNS
THE SPINAL CORD • Shape: cylindrical • Position:occupies the upper 2/3 of vertebral canal • Origin:continuation of medulla oblongata through the margin of foramen magnum • Termination: • In adult life: it narrows to form the conus medullariswhich ends at the level of the disc between L1 & L2 • Until 3rd month of fetal life: it occupies the entire length of vertebral canal • At birth: it ends at the level of L3
THE SPINAL CORD • Segments:divided into 31 segments ( 8 cervical, 12 thoracic, 5 lumbar, 5 sacral & 1 coccygeal) • Attachments:each segment is attached to a pair of spinal nerves • Enlargements: • Cervical (C3 to T1): gives the brachial plexus supplying the upper limb • Lumbar (L1 to S3): gives lumbar & sacral plexus supplying the lower limb
THE SPINAL CORD • Cauda equina (horse’s tail):collection of lumbar, sacral & coccygeal nerves below the termination of the spinal cord • Filum terminale:a thin fibrous band extending from the tip of conus medullaris ( in the middle of cauda equina) to the dorsal surface of first coccygeal vertebra
Spinal nerves • Number:31 pairs (8 cervical , 12 thoracic, 5 lumbar, 5 sacral & 1 coccygeal) • Types of fibers:mixed (sensory + motor) • Site of exit from vertebral canal: • C1 to C7:leave above corresponding vertebrae. • C8: leaves below C7 vertebra. • T1 to L5: leave below corresponding vertebrae. • S1 to S4: Leave throughsacral foramina. • S5 & coccygeal nerve: leave throughsacral hiatus.
Constituents of a typical spinal nerve It is attached to spinal cord by 2 roots: • Dorsal (posterior) sensory root: formed of afferent neurones;their cell bodies are located in the dorsal root ganglia which appear as enlargements in the root near the intervertebral foramen. • Ventral (anterior) motor root: formed of efferent neurones;their cell bodies are located in the grey matter of spinal cord. Both roots unite to form the spinal nerve, just before its exit from intervertebral foramen.
Constituents of a typical spinal nerve After its exit: the spinal nerve divides into: • Dorsal (posterior) ramus: a small mixedbranch that supplies skin & muscles of the back. • Ventral (anterior) ramus: a larger mixedbranch that supplies skin & muscles of limbs and antero-lateral body walls.
SPINAL NERVE INJURY • Spinal nerves are exposed to compression by : • Spondylosis: degenerative changes in the joints of vertebral column • Prolapse of intervertebral discs • Prolapse is common is lumbar region leading to back pain radiating into the legs (sciatica)
Spinal meninges Dura matter: • Outer covering, thick & dense membrane • Separated from the periosteum of the vertebral column by a space called the epidural space containing loose fat & a plexus of veins (epidural or internal vertebral venous plexus) • Ends at the level of S2
Spinal meninges Arachnoid matter: • Translucent membrane, between the dura & pia matters • Separted from dura by a space called subdural space containing serous fluid acting as a bursa between the tough dura & the delicate arachnoid. • Separated from pia by a space called subarachnoid space containing cerebrospinal fluid & blood vessels. • Ends at level of S2
Spinal meninges • Both dura & arachnoid extend to form sleeves for ventral & dorsal roots extending as far as fusion of both roots to form the spinal nerves • They become continuous with the epineurium of the spinal nerve
LUMBAR PUNCTURE • The subarachnoid space is large below the level of termination of spinal cord (from L2 to S2). This site is a favorable site for lumbar puncture (best between L3 & L4 or L2 & L3)
Spinal meninges Pia matter: • Inner delicate, vascular, closely applied to spinal cord. • Along a line midway between the dorsal & ventral roots, the pia projects laterally to form denticulate ligaments that pass through arachnoid to be attached to dura.
Blood supply of spinal cord Arterial supply: • Longitudinal arteries:one anterior spinal & two posterior spinal arteries • Branches of 4th part of vertebral artery • Posterior spinal arteries may arise from posterior inferior cerebellar arteries • Run along the length of spinal cord (the anterior artery runs along the anterior median fissure, the posterior arteries run behind the dorsal roots) • Main supply for cervical part of spinal cord
Blood supply of spinal cord Arterial supply: 2)Transverse (Radicular) arteries: • Branches of segmental artery (vertebral, ascending cervical, posterior intercostal, lumbar arteries) • Enters through intervertebral foramen and divides into anterior & posterior branches running along the ventral & dorsal roots of the spinal nerve. • The great radicular artery (artery of Adamkiewicz): a particular large artery that may arise from intercostal or lumbar arteries (from T8 to L3) • Main supply of the spinal cord, below cervical levels
Blood supply of spinal cord Venous drainage: • Six longitudinal veins:one anterior, one posterior, two anterolateral & two posterolateral veins. • The veins drain into the anterior & posterior radicular veins which end into the internal vertebral venous plexus.
Disorders of blood supply • The anterior portion of spinal cord together with its arterial supply (anterior spinal artery) are more liable to be damaged in the thoracic region • Occlusion of anterior spinal artery leads to an acute thoracic cord syndrome with paraplegia & incontinence