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General Approach of Haemostasis

The Prothrombin Time (PT) will vary with the type of thromboplastin (e.g. rabbit, human, bovine etc) used in the assay. This difference in sensitivities is known as the sensitivity index.Individual thromboplastins can be calibrated against an international WHO reference thromboplastin (Internation

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General Approach of Haemostasis

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    1. General Approach of Haemostasis Prothrombin Time (ISI and INR)

    2. The Prothrombin Time (PT) will vary with the type of thromboplastin (e.g. rabbit, human, bovine etc) used in the assay. This difference in sensitivities is known as the sensitivity index. Individual thromboplastins can be calibrated against an international WHO reference thromboplastin (International Reference Preparation or IRP) to assign them an International sensitivity index or ISI. The first WHO reference thromboplastin was assigned an ISI of 1.0 Introduction

    15. Next Lecture: aPTT (activated Partial Thromboplastin Time)

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