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The Digestive System: Overview of Organs and Processes

This chapter provides an overview of the digestive system, including the organs involved and the processes of digestion and absorption. It also discusses the regulatory mechanisms, peritoneum and peritoneal cavity, blood supply, and histology of the alimentary canal.

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The Digestive System: Overview of Organs and Processes

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  1. 1 CHAPTER 23 (8th edition) THE DIGESTIVE SYSTEM part 1

  2. 2. Digestive System • Two groups of organs • Alimentary canal (gastrointestinal or GI tract) • Digests and absorbs food • Mouth, pharynx, esophagus, stomach, small intestine, and large intestine

  3. 3. Digestive System • Accessory digestive organs • Teeth, tongue, gallbladder • Digestive glands • Salivary glands • Liver • Gall bladder • pancreas

  4. 4 Fig. 23.1 Pg 852 Parotid gland Mouth (oral cavity) Sublingual gland Salivary glands Tongue Submandibular gland Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Transverse colon Duodenum Descending colon Jejunum Small intestine Ascending colon Large intestine Ileum Cecum Sigmoid colon Rectum Vermiform appendix Anal canal Anus Figure 22.1

  5. 5. Digestive Processes • Six essential activities • Ingestion • Propulsion • Mechanical digestion (physical change) • Chemical digestion (chemical reactions , decomposition, surface area, new stuff) • Absorption • Defecation

  6. Fig. 23. Pg. 853 Ingestion Food Mechanical digestion Pharynx Esophagus • Chewing (mouth) Propulsion • Churning (stomach) • Segmentation (small intestine) • Swallowing (oropharynx) Chemical digestion • Peristalsis (esophagus, stomach, small intestine, large intestine) Stomach Absorption Lymph vessel Small intestine Blood vessel Large intestine Mainly H2O Feces Anus Defecation Figure 22.2

  7. 7Fig. 23.5a; page 855 From mouth (b) Segmentation: Nonadjacent segments of alimentary tract organs alternately contract and relax, moving the food forward then backward. Food mixing and slow food propulsion occurs. (a) Peristalsis: Adjacent segments of alimentary tract organs alternately contract and relax, which moves food along the tract distally. Figure 22.3

  8. 8. GI tract regulatory mechanisms SKIP • Intrinsic and extrinsic controls • Enteric nerve plexuses (gut brain) initiate short reflexes in response to stimuli in the GI tract • Long reflexes in response to stimuli inside or outside the GI tract involve CNS centers and autonomic nerves • Hormones from cells in the stomach and small intestine stimulate target cells in the same or different organs

  9. 9. Peritoneum and Peritoneal Cavity • Peritoneum: serous membrane of the abdominal cavity • Visceral peritoneum on external surface of most digestive organs • Parietal peritoneum lines the body wall • Peritoneal cavity • Between the two peritoneums • Fluid lubricates mobile organs

  10. Abdominopelvic cavity Vertebra Dorsal mesentery Parietal peritoneum Ventral mesentery Visceral peritoneum Peritoneal cavity Alimentary canal organ Liver (a) Schematic cross sections of abdominal cavity illustrate the peritoneums and mesenteries. Figure 22.5a

  11. 11. Peritoneum and Peritoneal Cavity • Mesentery is a double layer of peritoneum • Routes for blood vessels, lymphatics, and nerves • Holds organs in place and stores fat • Retroperitoneal organs lie posterior to the peritoneum • Intraperitoneal (peritoneal) organs are surrounded by the peritoneum

  12. 12 Fig. 23.5b; page 855 Mesentery resorbed and lost Abdominopelvic cavity Alimentary canal organ Alimentary canal organ in a retroperitoneal position (b) Some organs lose their mesentery and become retroperitoneal during development. Figure 22.5b

  13. 13. Blood Supply: Splanchnic Circulation Skip 13-24 • Arteries- that branch off the aorta and go to the digestive system and the hepatic portal system • Hepatic, splenic, and left gastric • Inferior and superior mesenteric • Hepatic portal circulation • Drains nutrient-rich blood from digestive organs • Delivers it to the liver for processing

  14. 14. Histology of the Alimentary Canal • Four basic layers (tunics) • 1. Mucosa • 2. Submucosa • 3. Muscularis externa • 4. Serosa

  15. 15 Fig. 23.6; page 857 Intrinsic nerve plexuses • Myenteric nerve plexus • Submucosal nerve plexus Glands in submucosa Mucosa • Epithelium • Lamina propria • Muscularis mucosae Submucosa Muscularis externa • Longitudinal muscle • Circular muscle Serosa Nerve • Epithelium Artery • Connective tissue Vein Lumen Gland in mucosa Lymphatic vessel Mucosa-associated lymphoid tissue Duct of gland outside alimentary canal Mesentery Figure 22.6

  16. 16. 1. Mucosa • Lines the lumen • Functions • Secretes mucus, digestive enzymes and hormones • Absorbs end products of digestion • Protects against infectious disease • Three sublayers: A. epithelium, B. lamina propria, and C. muscularis mucosae

  17. 17. Mucosa • A. Epithelium • Simple columnar epithelium and mucus-secreting cells • Mucus • Protects digestive organs from enzymes • Eases food passage • May secrete enzymes and hormones (e.g., in stomach and small intestine)

  18. 18. Mucosa • B. Lamina propria • Loose areolar connective tissue • Capillaries for nourishment and absorption • Lymphoid follicles (part of MALT) • C. Muscularis mucosae: smooth muscle that produces local movements of mucosa ???

  19. 19. 2. Submucosa • Submucosa • Dense connective tissue ??? • Blood and lymphatic vessels, lymphoid follicles, and submucosal nerve plexus ???

  20. 20. 3. Muscularis Externa • Responsible for segmentation and peristalsis • Inner circular and outer longitudinal layers • Myenteric nerve plexus ??? • Sphincters in some regions

  21. 21. 4. Serosa • Visceral peritoneum • Replaced by the fibrous adventitia in the esophagus skip • Retroperitoneal organs have both an adventitia and serosa skip

  22. 22 Fig. 23.6 page 857 Intrinsic nerve plexuses • Myenteric nerve plexus • Submucosal nerve plexus Glands insubmucosa Mucosa • Epithelium • Lamina propria • Muscularis mucosae Submucosa Muscularis externa • Longitudinal muscle • Circular muscle Serosa Nerve • Epithelium Artery • Connective tissue Vein Lumen Gland in mucosa Lymphatic vessel Mucosa-associated lymphoid tissue Duct of gland outside alimentary canal Mesentery Figure 22.6

  23. 23. Enteric Nervous System • Intrinsic nerve supply of the alimentary canal • Submucosal nerve plexus • Regulates glands and smooth muscle in the mucosa • Myenteric nerve plexus • Controls GI tract motility

  24. 24. Enteric Nervous System • Linked to the CNS via afferent visceral fibers • Long ANS fibers synapse with enteric plexuses • Sympathetic impulses inhibit secretion and motility • Parasympathetic impulses stimulate

  25. 25. Mouth • Oral (buccal) cavity • Bounded by lips, cheeks, palate, and tongue • Oral orifice is the anterior opening • Lined with stratified squamous epithelium

  26. 26 Fig. 23.7a Page 857 Soft palate Palatoglossal arch Uvula Hard palate Palantine bone Palantine process of maxillla Oral cavity Palatine tonsil Tongue Oropharynx Lingual tonsil Epiglottis Hyoid bone Laryngopharynx Esophagus Trachea (a) Sagittal section of the oral cavity and pharynx Figure 22.7a

  27. 27. Lips and Cheeks • Contain orbicularis oris and buccinator muscles • Vestibule: recess internal to lips and cheeks, external to teeth and gums • Oral cavity proper lies within the teeth and gums • Labial frenulum: median attachment of each lip to the gum

  28. 28 Fig. 23.7b; page 859 Upper lip Gingivae (gums) Superior labial frenulum Palatine raphe Palatoglossal arch Hard palate Palatopharyngeal arch Soft palate Uvula Posterior wall of oropharynx Palatine tonsil Tongue Sublingual fold with openings of sublingual ducts Lingual frenulum Opening of submandibular duct Gingivae (gums) Vestibule Inferior labial frenulum Lower lip (b) Anterior view Figure 22.7b

  29. 29. Palate • Hard palate: palatine bones and palatine processes of the maxillae • Slightly corrugated to help create friction against the tongue • Soft palate: fold formed mostly of skeletal muscle • Closes off the nasopharynx during swallowing • Uvula projects downward from its free edge

  30. 30. Tongue • Functions include • Repositioning and mixing food during chewing • Formation of the bolus • Initiation of swallowing, speech, and taste • Intrinsic muscles change the shape of the tongue • Extrinsic muscles alter the tongue’s position • Lingual frenulum: attachment to the floor of the mouth

  31. 31. Tongue • Surface bears papillae • taste buds • Diagram

  32. Epiglottis Palatopharyngeal arch Palatine tonsil Lingual tonsil cluster of lymphoid follicles Palatoglossal arch Terminal sulcus 32 Fig. 23.8 Page 860 Foliate papillae Circumvallate papilla Midline groove of tongue Dorsum of tongue Fungiform papilla Filiform papilla Figure 22.8

  33. 33. Salivary Glands • Extrinsic salivary glands (parotid, submandibular, and sublingual)

  34. 34. Salivary Glands • Intrinsic (buccal) salivary glands are scattered in the oral mucosa - no ducts • Secretion (saliva) • Cleanses the mouth • Moistens and dissolves food chemicals • Aids in bolus formation • Contains enzymes that begin the breakdown of starch (amylase)

  35. 35. Salivary Glands • Parotid gland • Anterior to the ear external to the masseter muscle • Parotid duct opens into the vestibule next to second upper molar • Submandibular gland • Medial to the body of the mandible • Duct opens at the base of the lingual frenulum

  36. 36. Salivary Glands • Sublingual gland • Anterior to the submandibular gland under the tongue • Opens via 10–12 ducts into the floor of the mouth

  37. 37 Fig. 23.9 page 861 Tongue Teeth Parotid gland Ducts of sublingual gland Parotid duct Masseter muscle Frenulum of tongue Body of mandible (cut) Sublingual gland Posterior belly of digastric muscle Mylohyoid muscle (cut) Submandibular duct Anterior belly of digastric muscle Submandibular gland Mucous cells Serous cells forming demilunes (a) (b) Figure 22.9

  38. 38. Composition of Saliva • Secreted by serous and mucous cells • 97–99.5% water, slightly acidic solution containing • Salivary amylase and lingual lipase PLAY Animation: Rotatable head

  39. 39. Control of Salivation • Intrinsic glands continuously keep the mouth moist • Extrinsic salivary glands produce secretions when • Ingested food stimulates chemoreceptors and mechanoreceptors in the mouth - Smell • Strong sympathetic stimulation inhibits salivation and results in dry mouth (xerostomia)

  40. 40. Teeth • Primary and permanent dentitions are formed by age 21 • 20 deciduous teeth erupt (6–24 months of age) • Roots are resorbed, teeth fall out (6–12 years of age) as permanent teeth develop • 32 permanent teeth • All except third molars erupt by the end of adolescence

  41. 41 Figure 23.10; page 862 (b) Deciduous teeth Permanent teeth Figure 22.10b

  42. 42. Classes of Teeth • 2I, 1C, 2P, 3M • Incisors • Chisel shaped for cutting • Canines • Fanglike teeth that tear or pierce • Premolars (bicuspids) and • Molars • Have broad crowns with rounded cusps for grinding or crushing

  43. 43 Figure 23.10; page 863 Incisors Incisors Central (7 yr) Central (6–8 mo) Lateral (8 yr) Lateral (8–10 mo) Canine (eyetooth) (11 yr) Canine (eyetooth) (16–20 mo) Premolars (bicuspids) Molars First molar (10–15 mo) First premolar (11 yr) Deciduous (milk) teeth Second molar (about 2 yr) Second premolar (12–13 yr) Molars First molar (6–7 yr) Second molar (12–13 yr) Third molar (wisdom tooth) (17–25 yr) Permanent teeth (a) Figure 22.10a

  44. 44. Tooth Structure • Crown: the exposed part above the gingiva (gum) • Covered by enamel—the hardest substance in the body (calcium salts and hydroxyapatite crystals) • Root: portion embedded in the jawbone • Connected to crown by neck

  45. 45. Tooth Structure • Cementum: calcified connective tissue • Covers root and attaches it to the periodontal ligament • Periodontal ligament • Forms fibrous joint called a gomphosis • Gingival sulcus: groove where gingiva borders the tooth

  46. 46. Tooth Structure • Dentin: bonelike material under enamel • Maintained by odontoblasts of pulp cavity • Pulp cavity: cavity surrounded by dentin • Pulp: connective tissue, blood vessels, and nerves • Root canal: extends from pulp cavity to the apical foramen of the root

  47. Enamel Dentin Crown Dentinal tubules Pulp cavity (contains blood vessels and nerves) Neck Gingiva (gum) Cementum 47 Figure: 23.11 Page: 863 Root canal Root Periodontal ligament Apical foramen Bone Figure 22.11

  48. 48. Tooth and Gum Disease Skip 48 through 50 - FYI only • Dental caries (cavities): gradual demineralization of enamel and dentin • Dental plaque (sugar, bacteria, and debris) adheres to teeth • Acid from bacteria dissolves calcium salts • Proteolytic enzymes digest organic matter • Prevention: daily flossing and brushing

  49. 49. Tooth and Gum Disease • Gingivitis • Plaque calcifies to form calculus (tartar) • Calculus disrupts the seal between the gingivae and the teeth • Anaerobic bacteria infect gums • Infection reversible if calculus removed

  50. 50. Tooth and Gum Disease • Periodontitis • Immune cells attack intruders and body tissues • Destroy periodontal ligament • Activate osteoclasts • Consequences • Possible tooth loss, promotion of atherosclerosis and clot formation in coronary and cerebral arteries

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