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8 September 2014 7:05 AM

2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated). 8 September 2014 7:05 AM. Spectinomycin. Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome. Spironolactone. Potassium sparing diuretic Antiandrogen

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8 September 2014 7:05 AM

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  1. 2004-2005Pharmacology Reviewof Everything(Principles, Cardiovascular and Respiratory drugs have been updated) 8 September 20147:05 AM

  2. Spectinomycin • AntibioticBacteriostatic protein synthesis inhibitor • 30S ribosome

  3. Spironolactone • Potassium sparing diureticAntiandrogen • Aldosterone receptor antagonistAndrogen receptor antagonistTestosterone synthesis inhibitorAntihypertensiveHeart failure treatment

  4. St. John’s Wort • Dietary supplement • Antidepressant

  5. Streptokinase • Thrombolytic

  6. Streptomycin • Aminoglycoside antibioticBactericidal protein synthesis inhibitor • 30S ribosomeFreezes initiation

  7. Succinylcholine • Paralytic • Depolarizing blockerParalyzes skeletal musclesBronchoconstrictor

  8. Sucralfate • Antiulcer

  9. Sufentanil • OpioidGeneral anaesthetic • Intravenous anaesthetic

  10. Sulfacetamide • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor • Inhibits dihydropteroate synthetaseTopical

  11. Sulfadoxine • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor • Dihydropteroate synthetase inhibitor

  12. Sulfamethoxazole • Sulfonamide antibioticMicrobial nucleic acidand protein synthesis inhibitor • Inhibits dihydropteroate synthetase

  13. Sulfasalazine • Disease modifyinganti-rheumatic drug (DMARD) • Metabolized to sulfonamide+ salicylate (NSAID)Treatment of IBD

  14. Sulfinpyrazone • Uricosuric • Anti-gout

  15. Sulfisoxazole • Sulfonamide antibioticNucleic acid andprotein synthesis inhibitor • Inhibits dihydropteroate synthetase

  16. Sulfonamides • AntibioticsNucleic acid andprotein synthesis inhibitors • Inhibit dihydropteroate synthetase

  17. Sulindac • NSAIDAnalgesic, Anti-inflammatory, Antipyretic • Cyclooxygenase inhibitor

  18. Suramin • Tropical antiparasitic • Treatment of African Trypanosomiasis

  19. Tacrolimus • ImmunosuppressiveAntineoplastic • Binds FKBP (FK506 binding protein)Inhibits calcineurin

  20. Tamoxifen • Antineoplastic Antiestrogen • Estrogen receptor anatagonist

  21. Tegaserod • IBS treatment • 5HT4 receptor agonist

  22. Telmisartan • Antihypertensive • Angiotensin receptor blocker(ARB)

  23. Temazepam • Sedative/Hypnotic • Benzodiazepine Acts on GABAA receptor complex

  24. Tenecteplase • Thrombolytic • Tissue plasminogen activator (tPA)

  25. Terazosin • Sympatholytic1adrenergic antagonist • AntihypertensiveTreatment for benign prostatic hypertrophy

  26. Terbinafine • Allylamine antifungal • Inhibits ergosterol synthesis by inhibiting squalene epoxidase

  27. Terbutaline • Sympathomimetic2 adrenergic agonist • Short acting bronchodilator TocolyticUterine relaxant

  28. Testosterone • Androgen • Natural male gonadal steroid

  29. Testosterone cypionate • Androgen • Synthetic depot

  30. Testosterone enanthate • Androgen • Synthetic depot

  31. Testosterone propionate • Androgen • Synthetic depot

  32. Tetracaine • Local anaesthetic

  33. Tetracycline • AntibioticBacteriostatic protein synthesis inhibitor Antiulcer • 30S ribosomePrevents aminoacyl tRNA attachment

  34. Thalidomide • AntineoplasticLeprosy treatment • Anti-angiogenicAnti-TNF

  35. Theophylline • Bronchodilator • MethylxanthinePhosphodiesterase inhibitorUsed in asthma

  36. Thiabendazole • Antihelminthic • Treatment of intestinal roundworms

  37. 6-Thioguanine • Antineoplastic • Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

  38. Thiopental • General Anaesthetic • Ultra-short-acting barbiturate

  39. Thioridazine • Antipsychotic • Phenothiazine

  40. Thiotepa • Antineoplastic • Alkylating agent

  41. Thiothixene • Antipsychotic

  42. Thrombopoietin • Cytokine • Platelet synthesis stimulator

  43. Thromboxane A2 (TXA2) • Autacoid • Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

  44. Thyrotropin-releasing Hormone (TRH) • Hypothalamic hormone • Stimulates release of thyroid stimulating hormone (TSH) from the anterior pituitary

  45. ThyrotropinThyroid-stimulating Hormone (TSH) • Anterior pituitary hormone • Stimulates production of thyroxine (T4), triiodothyronine (T3) and thyroglobulin

  46. Ticarcillin • Penicillin antibioticCell wall synthesis inhibitor • Anti-pseudomonal penicillinInhibits peptidoglycan cross-linking

  47. Ticlopidine • Antiplatelet • ADP receptor antagonist

  48. Timolol • Sympatholytic adrenergic antagonist • AntihypertensiveGlaucoma treatmentAnti-anginalBronchoconstrictor

  49. Tissue plasminogen activators alteplase, reteplase, tenecteplase • Thrombolytics

  50. Tobramycin • Aminoglycoside antibioticBactericidal protein synthesis inhibitor • 30S ribosomeFreezes initiation

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