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Areas of Expertise

Areas of Expertise. Enzyme. S. NMR- based Metabolomic. P. P. Biomimetic/bioinspired models. c-DNA. S. Biodiversity. Scale-up processes. Industrial applications. Thematic groups and Projects. S. Caldarelli. Organic / inorganic chemistry. Spectroscopy. V. Alphand. RMN. BioCat.

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Areas of Expertise

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  1. Areas of Expertise Enzyme S NMR-basedMetabolomic P P Biomimetic/bioinspired models c-DNA S Biodiversity Scale-up processes Industrial applications

  2. Thematic groups and Projects S. Caldarelli Organic/inorganic chemistry Spectroscopy V. Alphand RMN BioCat Metabolism Enzymology J. Perrier GlycoSI SAMBAS Biochemistry Cellular biology T. Tron Molecular biology

  3. Glycosydases in IntegratedSystems(GlycoSI) J. Perrier (PR), T. Giardina (PR), M. Fons (PR), Marc Maresca (MCF) et C. Nicoletti (IE) • Studies of the R. gnavus E1 glycobiome • IMAPIST, Metabolomic studies (ANR JCJC, L. Shintu 2012-14) • RumBa, M. Fons in collaboration with M. Atta (CEA Grenoble), S. Lavielle (ENS Paris) et F. Guerlesquin (IMM, Marseille)

  4. Metallic Active Sites in Biology and Synthetic Analogues (SAMBAS) T. Tron (CR), El H. Ajandouz (MCF), M. Attolini (MCF), P. Brouant (MCF), V. Desseaux (MCF), B. Faure (MCF), R. Hardré (MCF), M. Maffei (PR), Y. Mekmouche (CR), M. Réglier (DR), V. Robert (MCF), P. Rousselot-Pailley (CR) et J. Simaan (CR) S2 P2 Biomimetic/bioinspired Models Hybrid Artificial Enzyme M2 S P M M M1 S P S1 P1 NiFeCat (ANR Blanc, 2010-13) ; PhotoLac (PACA, 2010-13) ; ERECA (ANR JCJC, 2008-12) ; CUPA (ANR JCJC, 2009-12) et BICAB (ANR Blanc, 2009-12)

  5. Biocatalytic systems for sustainable chemistry (BioCat) V. Alphand (CR), A. Archelas (DR), V. Deyris (MCF) et G. Iacazio (PR) Substrate Product Synthetic substrates Natural substrates Renewable C-sources New products New biocatalists • NaturaDyRe (ANR CD2I, 2010-14) : Baeyer-Villigerases • BioSF (OSEO 2010-13) : Cyclopropanases et Lipoxygenases Cyclopropane synthase LOX/HPOD Non-allergenic aromatic molecules Fatty acids Green flavors

  6. Methodologies and Applications in NMR S. Caldarelli (PR), M. Campredon (PR), L. Shintu (MCF) et F. Tranchida (T) Methodology • Chromatographic NMR • ANR Blanc (2008-11) • APO-G Région PACA (2009-12) Metabolomic • Pre-clinical analysis (Univ. Franco-Italienne), plants (PIR Amazonie), food products (Comté), fraud, animal models with the GlycoSI thematic group (metabolic activities and bacterial symbiosis). • Project IMAPIST ANR JCJC L. Shintu (2012-14) • Establishment of the Center for Metabolomics (UMR INRA 1260/INSERM 1025 )

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