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In Vivo Dosimetry of Tomotherapy: Verification with Dosimetry Check Software

Learn about Reggio Emilia's experience using Dosimetry Check for Tomotherapy treatment plan verification. Explore configurations, measurements, dose kernels, DVHs, and gamma analysis. Compare TPS and DC computed doses with 2D arrays. See case studies on brain, prostate, head & neck, and thorax treatments.

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In Vivo Dosimetry of Tomotherapy: Verification with Dosimetry Check Software

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  1. In-vivoverificationofTomotherapy treatment planusing the DosimetryCheck software. The Reggio Emilia experience E. Mezzenga, E. Cagni, A. Botti, M. Orlandi, M. Iori MedicalPhysicsUnit, ASMN-IRCCS of Reggio Emilia, Italy (mezzenga.emilio@asmn.re.it)

  2. DOSIMETRY CHECKTM : configuration Clinicalbeamprofilemeasurementsfromacceptance test measurements (ATP) (example case forfieldwidth 1cm) Gaussianmonoenergatic dose kernel Modelling New photonicspectra (f) NO FitTomotherapy dose kernelfinalresultsforallfieldwidth Minimizing the costfunctions(f)betweenmeasured and computedPercentDepth Dose (PDD) Polyenergetic dose kernel (notgaussian) YES

  3. Phantom test: voxeldimension and comparisonwithconventional detector Choiceof the voxeldimensionfor dose computationperformedby DOSIMETRY CHECK.: DVHscomparison agreement 5 mm 2D dose comparisonperfomedbymeansofVerisoft v 4.2 between DC, TPS and 2Darray dose forin-vivosimulationsituation 3 mm TPS (blue) DC (green) dose distributioncomparison, considering a Tomotherapy IMRT verification test Best agreement between DC computed and 2Darray measured dose! 2 mm

  4. In-vivosimulationof a prostate treatment performed on 2Darray/OCTAVIUS Iso_Plan Point 1 Point 2 Point 3 Point 4

  5. Gamma analisys: metric used in Verisoft TPS dose vs 2Darray measurement DVH comparison between TPS (dotted) and DC (continuous) DC computed dose vs 2Darray measurement

  6. In-vivodosimetryofpatient-specificTomotherapy treatment plans: • Brain • Prostate • Head & neck • Thorax • consideredduring the first sessionoftheir treatment session.

  7. 3D Isodose linecomparison (magenta TPS, green DOSIMETRY CHECK). Transverseview Sagittalview Coronalview Brain Lineprofiles (dotted TPS, continuous DOSIMETRY CHECK) along the dotted yellow line in the corresponding upper view. 3D gamma analysis 3D gamma analysis

  8. 3D Isodose linecomparison (magenta TPS, green DOSIMETRY CHECK). Transverseview Sagittalview Coronalview Prostate Lineprofiles (dotted TPS, continuous DOSIMETRY CHECK) along the dotted yellow line in the corresponding upper view. 3D gamma analysis

  9. 3D Isodose linecomparison (magenta TPS, green DOSIMETRY CHECK). Transverseview Sagittalview Coronalview Head & neck Lineprofiles (dotted TPS, continuous DOSIMETRY CHECK) along the dotted yellow line in the corresponding upper view. 3D gamma analysis

  10. 3D Isodose linecomparison (blue TPS, green DOSIMETRY CHECK). Transverseview Sagittalview Coronalview Thorax Lineprofiles (dotted TPS, continuous DOSIMETRY CHECK) along the dotted yellow line in the corresponding upper view. 3D gamma analysis

  11. In-vivodosimetryof a head & neckpatient-specificTomotherapy treatment plan: MVCT merged on planning kVCT 3D Isodose linecomparison (blue TPS, green DOSIMETRY CHECK). Transverseview Sagittalview Coronalview DVH comparisonbetween TPS (dotted) and DC (dashed) using the planning kVCT Planning kVCT a) 3D gamma analysis DVH comparisonbetween TPS (dotted) and DC (continuous) using the planning kVCTmergedwith the MVCT acquiredafter the first treatment session Treat.#1 MVCT

  12. The results here shown represent a summary of those shown at: Forthcoming pubblication: E.Mezzenga et al., JINST, April 2014: “Pre-treatment and in-vivo dosimetry of Helical Tomotherapy treatment plans using the Dosimetry Check system” Acknowledgments W.D. Renner, Peter Myshrall MathResolution LLC, Columbia, MD, USA A. Peroni, D. Raspanti, L.Valli TemaSinergie spa, Faenza, Italy

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