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FOLLOW UP IN THALASSEMIA CLINIC

FOLLOW UP IN THALASSEMIA CLINIC. Presented by: Dr. Afsana Jahan (PGT) Dr. Aditi Baruah (MD); Dr. P. Bishwanath (MD) Department of Paediatrics Assam Medical College & Hospital, Dibrugarh. Introduction.

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FOLLOW UP IN THALASSEMIA CLINIC

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  1. FOLLOW UP IN THALASSEMIA CLINIC Presented by: Dr. Afsana Jahan(PGT) Dr. Aditi Baruah (MD); Dr. P. Bishwanath (MD) Department of Paediatrics Assam Medical College & Hospital, Dibrugarh

  2. Introduction • Thalassemia is the commonest chronic haematological disease needing repeated blood transfusion. • North-East specially Assam is a reservoir of abnormal haemoglobins & also thalassemia because of ethnic diversity of the inhabitants. • Present thalassemia clinic was established in April’2005, AMCH, Dibrugarh where regular follow-up of thalassemia pateints are done.

  3. Aim of the Study To study the follow-up cases of haemo-globinopathy with special reference to thalassemia in thalassemia clinic

  4. Materials & Methods • Place of Study : Thalassemia clinic, AMCH • Period of Study : May’2005 to Oct’2007 • Study universe : 50 diagnosed and registered cases of Haemoglobinopathy • Selection criteria : Cases of Haemoglobinopathy diagnosed by HPLC.

  5. Age & Sex distribution at registration

  6. Distribution of haemoglobinopathies

  7. Caste & Community distribution

  8. Showing status of spleen

  9. Photograph showing facial features and heptosplenomegaly

  10. Complications of Haemoglobinopathy

  11. PHOTOGRAPH SHOWING BONY CHANGES IN SKULL X-RAY

  12. Effect of chelation on Serum Ferritin

  13. Effect of use of filter on transfusion reaction

  14. Parental HPLC study

  15. Chromatogram

  16. Problems in Thalassemia clinic • Family study and convincing parents and relatives for necessity of the test. • Irregular follow-up visits. • Irregular blood transfusion • Lack of voluntary blood donation. • Cost of filters and chelation therapy limits their use. • Cost of different laboratory tests.

  17. Need of the HOUR! • Public awareness. • Education of health professional. • Antenatal diagnosis. • Emphasis on conventional treatment in particular chelation in view of its high efficacy. • Cure of the disease with increasing possibility of bone marrow transplantation and gene therapy. • Concrete support for achieving high standard for management of thalassemia in this part of Country.

  18. Conclusion Thalassemia clinic is playing an important role in making thalassemia a preventable, manageable and curable disease in prospect of high incidence in this region.

  19. THANK YOU & wish you all a very HAPPY NEW YEAR

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