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DNA REPLICATION

Explore the historic discovery of DNA's double helix structure by James Watson and Francis Crick in 1953. Learn about the composition of DNA, the role of nucleotides, and the process of DNA replication essential for cell division. Discover the significance of complimentary base pairing and the enzymes involved in DNA replication. Uncover the intricate mechanisms that ensure accurate replication of genetic information.

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DNA REPLICATION

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  1. DNA REPLICATION

  2. STRUCTURE DISCOVERY (don’t write!) • James Watson, Francis Crick • 1953

  3. DNA STRUCTURE • Deoxyribose Nucleic Acid • Repeating monomer (nucleotide): • Phosphate • Sugar • Base

  4. DNA STRUCTURE • Spiralling double helix • Complimentary bases pair up • Hydrogen bonds form between • Phosphate &sugar = backbone

  5. COMPLEMENTARY BASES • Purines • Adenine • Guanine • Pyrimidines • Cytosine • Thymine

  6. CELL DIVISION, DNA REPLICATION • Cells must divide (growth, repair, replace) • Before cells divide structures, organelles and DNA must be replicated • Each cells needs an exact, complete copy!

  7. DNA REPLICATION (DON'T WRITE!)

  8. DNA REPLICATION • Complimentary base pairing allows each strand to act as a template for the new strand • "Semiconservative" - new DNA is 1 parent, 1 new strand

  9. REPLICATION • Enzyme "helicase" unwinds and unzips helix

  10. REPLICATION • 2. Build new daughter strand • Line up base pairs • Enzyme : DNA polymerase

  11. REPLICATION • 3. Bond nucleotides together • Enzyme : DNA ligase

  12. TO DO'S • Provincial Qs and study guide questions • Dictionary • DNA polymerase, DNA ligase, semi conservative replication, helicase

  13. Overall Picture:

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