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Influenza and HIV/AIDS. Ida M. Onorato, M.D. National Center for HIV, STD and TB Prevention November 22, 2004. Influenza and HIV/AIDS. People living with HIV/AIDS (PLWHA) are at increased risk of serious complications from influenza
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Influenza and HIV/AIDS Ida M. Onorato, M.D. National Center for HIV, STD and TB Prevention November 22, 2004
Influenza and HIV/AIDS • People living with HIV/AIDS (PLWHA) are at increased risk of serious complications from influenza • These complications include prolonged symptoms, hospitalization, pneumonia and death
Influenza Vaccination • Influenza vaccination produces protective antibody and has been shown to be effective in PLWHA • But persons with severe immunosuppression may not mount an adequate antibody response • However, CD4 level is not clearly predictive of response or non-response to vaccination
Influenza Antivirals • Influenza antiviral medications may be used for treatment or considered for chemoprophlylaxis in certain circumstances • There are no published data on the the interactions between anti-infuenza drugs and HAART or other drugs used in HIV care
Recommendations • CDC/ACIP have issued recommendations for 2004- 2005 influenza season which include PLWHA and their care providers • CDC has scheduled this special briefing for organizations and persons who care for PLWHA on these recommendations
Recommendations • CDC/ACIP have issued recommendations for the 2004 –2005 influenza season which include PLWHA and their care providers • CDC has scheduled this special briefing for organizations and persons who care for PLWHA on these recommendations