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IL-4

400. 350. 300. 250. 200. 150. 100. 50. 0. 600. 100. 30. 500. 25. 80. 400. 20. 60. 300. 15. 40. 200. 10. 20. 100. 5. 0. 0. 0. c. 1. 0. 0. 0. IL-22. 160. 1. 0. 0. 140. 120. mRNA level to HPRT (x10 -3 ). 100. 1. 0. 80. mRNA level to HPRT (x10 -3 ). 60.

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IL-4

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  1. 400 350 300 250 200 150 100 50 0 600 100 30 500 25 80 400 20 60 300 15 40 200 10 20 100 5 0 0 0 c 1 0 0 0 IL-22 160 1 0 0 140 120 mRNA level to HPRT (x10-3) 100 1 0 80 mRNA level to HPRT (x10-3) 60 40 1 20 I L - 1 7 A I L - 1 7 F I L - 2 2 A h R 0 iTreg Th17 Th0 Th1 Th2 Figure 1 a Tbet GATA3 RORg AHR B6 AhR-/- iTreg iTreg iTreg Th2 iTreg Th17 Th0 Th1 Th2 Th17 Th0 Th1 Th17 Th0 Th1 Th17 Th0 Th1 Th2 Th2 mRNA level to HPRT (x10-3) IFNg IL-4 IL-17A IL-17F 1000 6000 12000 10000 5000 800 10000 8000 4000 8000 600 6000 3000 6000 400 4000 2000 4000 200 2000 1000 2000 0 0 0 0 iTreg iTreg iTreg iTreg Th17 Th17 Th17 Th0 Th1 Th2 Th0 Th2 Th0 Th1 Th2 Th1 Th0 Th1 Th2 Th17 b

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