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Obtaining & handling AEFI data from surveillance systems. AEFI data management training course. Aspects discussed. The AEFI surveillance cycle and key players. - National/ Subnational prgm. mgr. - Health worker. - Caregiver - Health worker. AEFI committee.
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Obtaining & handling AEFI data from surveillance systems AEFI data management training course
The AEFI surveillance cycle and key players - National/ Subnational prgm. mgr. - Health worker - Caregiver - Health worker AEFI committee Surveillance: The ongoing systematic collection and analysis of data and the provision of information which leads to action National/ Subnational programme manager - Health worker - District level manager
AEFI Surveillance system Objectives Depending on the local context, define what is the purpose of the surveillance system and what is intended to be monitored (for example a system to detect - ALL AEFI, Serious AEFI, Events of Special interest or events related only to new vaccines introduced, etc) Roles and responsibilities • Who will identify the AEFI and collect information • Who and where to report, and timeline • Who and how to process data and analyze • Who will monitor the outputs of the system and periodicity
Passive AEFI surveillance system • Recognition • Encouraging Reporting • Use of forms and procedures • For corrective action • To reinforce usefulness of reporting • To reassure patients and HCWs
Passive surveillance: AEFI Routing, Timeline and Actions Health Worker (Primary or Hospital) Site Complete first part of report form Immediate report in reporting form • Confirm AEFI, Assign code number, complete ALL details in the reporting form and e mail to EPI • Dist level planning meeting on investigation • Investigate the AEFI case (ask IPH for help only if necessary) • Complete the investigation form • Initiate collection of Medical report, vaccine, logistic samples, Laboratory report eg CSF, Serum (or other biological products) Example District public health authority District • For completed reporting form 24 Hours (e mail) • For investigation form 7 days (Hard copy with supporting doc) National • Immediately review reporting form and see if addl cases occurred in other places of the country • With report form, create national linelist and national database to share with MoH • Support field investigation if needed • Analyze the investigation form, consult with AEFI expert committee if needed. Send inv form to NRA • Upload data to WHO UNICEF JRF after approval by MoH EPI WHO UNICEF JRF Investigation form within 7 days of completing field investigation AEFI Committee NRA Vigiflow • Upload data to Global database (Vigiflow) after approval from MoH • If needed • Inform UNICEF and MAH (with copy to MoH) • Inform manufacturer and authorized importers (with copy to MoH) National linelist MoH (Ministry of health) Note: Timelines indicated are upper limits Feedback Global sharing after approval
Standardized forms • Collect relevant data in a specific format • In accordance with the surveillance objectives • In compliance with regulatory requirements • Allows for efficient and complete data processing, analysis and reporting • Facilitates the exchange of data across projects and organizations, esp. through standardization • Design should met users demands, avoid duplication and be clear and simple
The AEFI reporting and linelisting form Key forms for data analysis
Steps for data analysis Tabulation - by place, person, time, antigens and type of event Completing the AEFI reporting form for ALL events that have been brought to the notice of the health care system Linelisting - will help initial identification of clustering or any unusual or significant reporting events that need further analysis Analysis: Time, place and person Calculating the relevant rates using correct denominators and multipliers Comparing the rates ie expected vs observed • AEFI rates • Reported AEFI rates for each antigen in a given time period (month, quarter-year or year). • AEFI rates by first, second or third dose if the antigen is administered more than once. • AEFI by the location of occurrence • AEFI by the type of event • AEFI by seriousness
Quick analysis with forms received … • Define the extent of the problem • Time: What are the dates of onset of cases? • Place: Where do cases originate from? • Person: Who are they? • Number of AEFI reports received monthly (serious and non serious AEFIs including clusters) • Estimating rates (per 1000, 10,000 or 100,000 – by vaccine or event) and comparing with known rates • Classification of reported AEFI by types • Classification of AEFI by antigen • Classification of events by causality assessment • Unusual AEFI
Routine data analyzed can provide information on Increase in the number of AEFI reported Geographic location of the cases Identifying clusters Ad-Hoc analysis Helpful when new issues have been identified by the system Retrospective analysis may reveal that similar problem existed before What can a quick look at data tell us?
Data monitoring, quality control and feedback Program managers should keep track (monitor), identify issues (quality control) and intervene (provide feedback) on • Data generation • Data Flow • Data Quality • Data Cleaning • Data Analysis • Timeliness and completeness • Country relevant performance indicators
Suggestions: Local level data analysis Who should analyse data: The person need not be a data management specialist, instead it could be any person in charge of immunization program implementation
Suggestions: Subnational level data analysis Who should analyse data: The person need may or may not be a data management specialist, instead it could be any person in charge of decision making
Suggestions: National level data analysis Who should analyse data: The person should ideally be a data management specialist, the data analysed should be processed and presented to the decision making authority