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Coaxial needle less electrospinning

Coaxial needle less electrospinning. Ing. Lucie Vysloužilová Prof. RNDr. David Luk áš , CSc. Coaxial electrospinning. Special method for bicomponent core/shell nanofibers production Shell – mostly polymer material Core – polymer of nonpolymer material, liquid, encapsulated materials

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Coaxial needle less electrospinning

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  1. Coaxialneedleless electrospinning Ing. Lucie Vysloužilová Prof. RNDr. David Lukáš, CSc.

  2. Coaxial electrospinning • Special method for bicomponent core/shell nanofibers production • Shell – mostly polymer material • Core – polymer of nonpolymer material, liquid, encapsulated materials • Hollow nanofibers • Possibility of nonspinnable • materials electrospinning shell core

  3. Coaxial needle electrospinning • Droplet, oneTaylorcone, one polymer jet • Lowproductivity a) co-axialspinner b) feedingofshellmaterial c)feedingofcorematerial d)drop e)polymer jet f) groundedcollector

  4. Coaxial needle less electrospinning • Polymericbi-layer • More Taylorcones more polymer jets • Procutivityincreasment a)layerof „core“ material b) layerof „shell“ material c, d) Taylorcone e) polymer jet f) groundedcollector g)highelectricalvoltage source

  5. Coaxialneedleless electrospinning -basin • Shell: 12% PVA • Core: oil 12%PVA/oil 12%PVA+dye/oil

  6. Optical microscope • Basin from nonconductive material • Shell: 12% PVA + dye • Core: oil

  7. Optical microscope • Basin from nonconductive material • Shell: 12% PVA + dye • Core: oil 50 µm 50 µm

  8. Weir spinner • A new device for bicomponent nanofibers production • Needle-less electrospinning • Principle: the bi-layer overflowing through electrode

  9. Weir spinner (a)Weir spinner (b) Holder (c) Feeding of shell material (d) Feeding of core material (e) Holder of cable from high voltage source

  10. Shell: 12% PVA + dye + rhodamin • core: 10% PVA + fitc dextran

  11. Confocal scanning microscopy 100 µm 100 µm Core:10% PVA + rhodamin Shell: 12% PVA + fitc dextran

  12. Advantagesofneedle-lesscoaxial electrospinning technology • Production of bicomponent core/shell nanofibers • Production of hollow fibers • Encapsulation – drug delivery systems • Electrospinning of nonspinnable materials by common electrospinning technology • Increasing productivity • Easy cleaning of the spinner

  13. Thank you for your attention!

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