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The limbic system

The limbic system. Neuronal circuitry controls of emotional behavior and motivational drives Composed of subcortical and cortical components. Limbic System. Figure 12.18. limbic. Subcortical group.

judah-potts
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The limbic system

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  1. The limbic system • Neuronal circuitry controls of emotional behavior and motivational drives • Composed of subcortical and cortical components

  2. Limbic System Figure 12.18

  3. limbic

  4. Subcortical group Hypothalamus ,septum,paraolfactory area,epithalamus,ant.thalamic nuclei,hippocampus,amygdala,basal gangeli

  5. Limbic cortex • Orbitofrontal coretx,subcallosal gyrous cingulate gyrus and parahippocamp gyrous

  6. Limbic System: Emotion and Cognition • The limbic system interacts with the prefrontal lobes, therefore: • One can react emotionally to conscious understandings • One is consciously aware of emotion in one’s life • Hippocampal structures – convert new information into long-term memories

  7. The hypothalamus not only influences how you feel, it influences how you interpret the consequences of those feelings.

  8. limbic

  9. Hypothalamic Role in Emotion HypothalamicNuclei VisceralAfferents HormonalOutput Nucleusof the Solitary Tract TargetOrgans AutonomicOutput AutonomicPreganglionicNuclei Brain StemNuclei

  10. Hypothalamus PituitaryReleasing Factors AutonomicNervous System Sympathetic Neurohypophysis(Posterior Pituitary) Adenohypophysis(Anterior Pituitary) Parasympathetic

  11. “I feel fear!”

  12. striaterminalis Amygdala mtt Anterior Nucleus dorsal long.fasciculus Brainstem medial forebrainbundle Cortex, septum Hypothalamus ventralroute medialforebrainbundle Brainstemspinal cord Amygdala parvo magno(SO, PV) ant. post. Pituitary

  13. Hypothalamus,Major • Hypothalamus is the most important output sorce • It communicate with brain stem by medial forebrain bundle ,bidirectionaly between forebrain and brain stem

  14. Hypothalamus cont. • Controls: 1-vegetative and endocrine functions 2-behavior and motivation

  15. vegetative and endocrine functions • Cardiovascular regulation involves 1-Post. And lateral hypothalamus area, increase BP and HR. 2-preoptic area ,decrease BP and HR *1and 2 mediated by cardiovascular centre in the pontile and medullary part of reticular formation

  16. Body temperature regulation • Preoptic area

  17. Thermo-regulation (body temperature) • Involves autonomic nervous, endocrine, and skeletomotor systems • Body temperature detectors • Peripheral: skin, spinal cord, viscera • Central: anterior hypothalamus • Body temperature effectors • Heat retention or generation: posterior hypothalamus • Heat dissipation: anterior hypothalamus

  18. Thermo-regulation (body temperature) • Heat dissipating mechanisms • Dilation of blood vessels in the skin • Inhibition of shivering • Heat conserving mechanisms • Vasoconstriction of blood vessels in the skin • Shivering • Increased secretion of thyroxin

  19. Response to Cold Response to Heat Methods of thermo-regulation by the body

  20. Regulation of body water intake • Thirst centre,lateral hypothalamus • Electrolyte concentrationmaking desire to drink • Supraopticx:urinary excrition due to ADH

  21. Thirst • Function of serum osmolality and blood volume • Osmotic receptors in the hypothalamus • Volume receptors in the right atrium of the heart and great veins • Vasopressin release from hypothalamus • Increases water reabsorption from the kidney • Inhibited by ethanol

  22. Circadian Rhythm • Oscillations during the course of the day • Corticosteriods • Feeding and drinking behavior • Growth hormone secretion • Lesions of the suprachiasmatic nuclei of the hypothalamus disrupts these oscillations

  23. Control of Feeding

  24. Feeding • Complex interaction of many systems • Regulation of energy metabolism by the Ventromedial and Lateral nuclei of the hypothalamus • Physical Lesions produce hyperphagia and obesity or reduced attention to food. • Amygdala may also be involved indirectly • Lesions produce hyperphagia-like symptoms • Ventromedial hypothalamic lesions also cause increased insulin secretion Obesity.

  25. Feedback Mechanisms Controlling Feeding • Feedback from gut hormones • e.g. Cholecystokinin • Released from small intestine in response to feeding • Inhibits or suppresses feeding

  26. Uterine contraction and milk ejection • Oxytocin stimulation by PARAVENTRICULAR

  27. هسته آميگدال و ارتباط آن با نواحي مختلف مغز

  28. ارتباطات عصبي سيستم ليمبيك

  29. ارتباطات اصلي شكنج سينگولا

  30. مسيرهاي پردازش اطلاعات

  31. Hippocampus circuit • Ent. cortex From perforant To dentate gyrous mossy fiber cA3 schaffer collaterals cA1 to subiculum to ento cortex

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