Lecture 12 Tuesday 2/12/08

1. Lecture 12 Tuesday 2/12/08 Multiple Reactions Selectivety and Yield Series Reactions Complex Reactions

2. Blood Coagulation Many metabolic reactions involve a large number of sequential reactions, such as those that occur in the coagulation of blood. Cut → Blood → Clotting Figure A. Normal Clot Coagulation of blood (picture courtesy of: Mebs, Venomous and Poisonous Animals, Medpharm, Stugart 2002, Page 305) Department of Chemical Engineering, University of Michigan, Ann Arbor

3. Schematic of Blood Coagulation Department of Chemical Engineering, University of Michigan, Ann Arbor

4. Cut A + B C D E F Clot Department of Chemical Engineering, University of Michigan, Ann Arbor

5. MODEL EQUATIONS: Department of Chemical Engineering, University of Michigan, Ann Arbor

6. MODEL EQUATIONS: Department of Chemical Engineering, University of Michigan, Ann Arbor

7. NOTATIONS Department of Chemical Engineering, University of Michigan, Ann Arbor

8. NOTATIONS Department of Chemical Engineering, University of Michigan, Ann Arbor

9. MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor

10. MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor

11. MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor

12. RESULTS Department of Chemical Engineering, University of Michigan, Ann Arbor

24. Multiple Reactions example: A → B → C (1) A → B (2) B → C 1) Mole balances: 2) Rates: rate laws: relative rates: 3) Combine:

25. When is CB the highest? Example: CSTR multiple reactions A → B → C what is the optimal ? 1) Mole Balance:

26. 2) Rates: laws: net: relative: 3) Combine:

27. Example: Liquid phase PFR A + 2B → C (1) 2A + 3C → D (2) 1) Mole balances: 2) Rates: laws: net: relative: 3) Stoich: overall selectivity: parameters: