270 likes | 335 Views
Lecture 12 Tuesday 2/12/08. Multiple Reactions Selectivety and Yield Series Reactions Complex Reactions. Blood Coagulation.
E N D
Lecture 12 Tuesday 2/12/08 Multiple Reactions Selectivety and Yield Series Reactions Complex Reactions
Blood Coagulation Many metabolic reactions involve a large number of sequential reactions, such as those that occur in the coagulation of blood. Cut → Blood → Clotting Figure A. Normal Clot Coagulation of blood (picture courtesy of: Mebs, Venomous and Poisonous Animals, Medpharm, Stugart 2002, Page 305) Department of Chemical Engineering, University of Michigan, Ann Arbor
Schematic of Blood Coagulation Department of Chemical Engineering, University of Michigan, Ann Arbor
Cut A + B C D E F Clot Department of Chemical Engineering, University of Michigan, Ann Arbor
MODEL EQUATIONS: Department of Chemical Engineering, University of Michigan, Ann Arbor
MODEL EQUATIONS: Department of Chemical Engineering, University of Michigan, Ann Arbor
NOTATIONS Department of Chemical Engineering, University of Michigan, Ann Arbor
NOTATIONS Department of Chemical Engineering, University of Michigan, Ann Arbor
MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor
MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor
MOLE BALANCE Department of Chemical Engineering, University of Michigan, Ann Arbor
RESULTS Department of Chemical Engineering, University of Michigan, Ann Arbor
Multiple Reactions example: A → B → C (1) A → B (2) B → C 1) Mole balances: 2) Rates: rate laws: relative rates: 3) Combine:
When is CB the highest? Example: CSTR multiple reactions A → B → C what is the optimal ? 1) Mole Balance:
2) Rates: laws: net: relative: 3) Combine:
Example: Liquid phase PFR A + 2B → C (1) 2A + 3C → D (2) 1) Mole balances: 2) Rates: laws: net: relative: 3) Stoich: overall selectivity: parameters: