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Upper Ontology Summit Wednesday March 15 The BFO perspective. Barry Smith Department of Philosophy, University at Buffalo National Center for Ontological Research National Center for Biomedical Ontology. Basic Formal Ontology.
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Upper Ontology SummitWednesday March 15The BFO perspective Barry Smith Department of Philosophy, University at Buffalo National Center for Ontological Research National Center for Biomedical Ontology http://ontologist.com
Basic Formal Ontology • BFO is a highest-common-denominator upper ontology designed to support interoperability between domain ontologies supporting shared use of scientific research data across disciplinary boundaries • BFO used and tested primarily within the biomedical domain; part of a collaborative effort with research groups and consortia supported by the NIH to make clinical trial data and model organism experimental data re-usable when diagnostic criteria or experimental hypotheses change http://ontologist.com
The core of BFO • importance of axioms and definitions • distinction between types and instances • the acceptance of both continuants and occurrents • the distinction between dependent continuants (for example: organisms) and dependent continuants (for example: qualities, functions, roles) http://ontologist.com
First key distinguishing mark • Data are primarily about instances • Ontologies are primarily about types • Compare A-box / T-box in Description Logics • instance-level relations • this cell nucleus adjacent_tothis cytoplasm • type-level relations • cell nucleus adjacent_to cytoplasm http://ontologist.com
Second key distinguishing mark • BFO allows quantification not only over instances but also over types (using the same individual variables for each) http://ontologist.com
BFO is very small • It strives to be the highest common factor ontology relative to those upper ontologies which are • (1) formally sufficiently robust to support data management needs of high-level scientific research • (2) sufficiently broad in scope to support cross-granular and cross-disciplinary alignment of domain ontologies • (3) sufficiently commonsensical to attract large numbers of users from the side of domain science http://ontologist.com
Why should an upper ontology be small? • Biologists need an upper ontology if they are to achieve domain ontology alignment. • This should be an upper ontology which they can understand and accept • They will not accept an upper ontology which embodies an axiomatic treatment of biological types (like monkey, vegetable, ...) http://ontologist.com
Reasons for axiomatization • Axiomatization and formal definitions at the top can help bring about advances towards logic-based reasoning when working with very large domain ontologies • But: axioms and definitions formulated exclusively in machine-understandable terms will not be used by those developing domain ontologies • Hence BFO is maintained in equivalent human-intelligible and machine-intelligible formats http://ontologist.com
OBO Foundry • OBO = Open Biomedical Ontologies Consortium (http://obo.sourceforge.net) • OBO Foundry = a subset of OBO ontologies which agree in advance to accept a common set of principles designed to assure formal robustness and interoperability* • Upper ontology of OBO Foundry project = shared common sense of biomedical scientists • *see “Relations in Biomedical Ontologies”, Genome Biology, Apr. 2005, http://genomebiology.com/2005/6/5/R46 http://ontologist.com
Conclusions • We need to distinguish the needs of ontology experts from those of ontology users • An upper ontology should be marked not merely by high formal rigor but also by conformity with human common sense http://ontologist.com