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RESPIT™ Regionally-specific immunotherapy

RESPIT™ Regionally-specific immunotherapy. Standardized allergen extracts defined by geographic region Inclusion based on Aerobiology Allergenicity Cross-reactivity. RESPIT Regions. Background evidence.

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RESPIT™ Regionally-specific immunotherapy

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  1. RESPIT™Regionally-specific immunotherapy • Standardized allergen extracts defined by geographic region • Inclusion based on • Aerobiology • Allergenicity • Cross-reactivity RESPIT Regions

  2. Background evidence • There is no consensus as to the most accurate testing technique, which display significant variability and in some cases poor reliability • Varied testing techniques and immunotherapy protocols produce similar results • Studies support the role of non-specific tolerance in humans • A double-blinded study found that stock mixture IT produced the same benefit as customized IT

  3. Garfield, R. Injection Immunotherapy in the Treatment of Canine Atopic Dermatitis:Comparison of 3 HyposensitizationProtocols. 1992, Members Meeting of the AAVD & ACVD, p. 7-8. Customized vs. Standardized Immunotherapy for Canine Atopic Dermatitis

  4. Comparison of standardized and allergen-specific IT Standardized ASIT • Allergy test required • Avoids false (-) and false (+) results • RCT supporting effectiveness • High-quality, placebo-controlled trials to establish efficacy • Guides allergen avoidance • Oral cavity & injectable administration available

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