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Clinical Research Management 512

Clinical Research Management 512. Leslie McIntosh lmcintosh@path.wustl.edu 314.747.7959 (office ). Agenda. Vocabulary Levels of Measurement Measures of Central Tendencies Study design types (overview). Vocabulary. Statistics Levels of Measurement Continuous

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Clinical Research Management 512

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  1. Clinical Research Management 512 Leslie McIntosh lmcintosh@path.wustl.edu 314.747.7959 (office)

  2. Agenda • Vocabulary • Levels of Measurement • Measures of Central Tendencies • Study design types (overview)

  3. Vocabulary • Statistics • Levels of Measurement • Continuous • Discrete (aka: Categorical) • Dichotomous • Nominal • Ordinal • Measures of Central Tendencies • Mean • Median • Mode • Range • Confidence Interval • p-Value

  4. Statistics • The study of inference – taking information from a small amount of data (sample) and making generalizations to a larger setting (population) • Extrapolating from a sample to a population

  5. Levels of Measurement (Variable Types) • Continuous – variables that can take on any value in a given range • Discrete (aka: Categorical) – variables that have a limited number of values • Dichotomous – two values • Nominal – multiple values where order does not matter • Ordinal – multiple values where order does matter

  6. Activity: Variable Types • What is your gender? • What is your age? • What is the highest level of education you have completed? • What is your own yearly income? • What is your total household income, including all earners in your household? • What is your current marital status? • What is your religious affiliation? • What is your race?

  7. Measures of Central Tendencies • Mean • Sum of all numbers divided by the total numbers within the distribution • Median • Midpoint of a distribution • Mode • Most frequent number in the distribution • Range • The spread of the distribution • The smallest number to the largest number

  8. Activity: Central Tendencies How much soda did you consume over the weekend?

  9. Study Designs • Descriptive • Analytic – hypothesis testing • Case reports • Case series • Ecologic (aka: correlational) • Cross-sectional • Case-control • Follow-up/cohort • Clinical trials

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