Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020

1. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Persistence Market Research Global E-Clinical Solution Software Market Will Reach US$ 6,515.3 million in 2020:Persistence Market Research Persistence Market Research 1

2. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Persistence Market Research Released New Market Report “Global Market Study on E- Clinical Solution Software: Asia to Witness Highest Growth by 2020”, the global e- clinical solution software market was valued at US$ 3,005 Mn in 2014 and is expected to expand at a CAGR of 13.8% from 2014 to 2020, to reach US$ 6,515.3 Mn by 2020. Browse the full report at : http://www.persistencemarketresearch.com/market-research/e- clinical-solution-market.asp The global e-clinical solution software market is witnessing significant growth due to increasing clinical trials and R&D investments in pharmaceuticals and life science sectors. Increasing prevalence of diseases across the world is leading to rise in number of clinical trials. Various lifestyle-associated diseases and genetic disorders in the Middle East and North Africa have also led to increase in clinical trials in the respective regions. In addition, the pharmaceutical industry is facing immense pressure to reduce the time consumed to conduct clinical trials and increase effect of drugs. Presence of various end users such as pharmaceuticals, clinical research organizations (CROs), and healthcare providers has increased the demand for e-clinical solution software. The global e-clinical solution software market was valued at US$ 3,005 Mn in 2014 and is expected to expand at a CAGR of 13.8% from 2014 to 2020 to reach US$ 6,515.3 Mn by 2020. Request Sample Report: http://www.persistencemarketresearch.com/samples/2884 In North America, the average cost of research and development for a successful pharmaceutical drug continues to increase from pre-clinical stage i.e. initial development stage of drug till FDA approval i.e. launch of the drug in the market. According to Oracle Corporation – an e-clinical software company – the share of global clinical trials conducted in North America has reduced from 30% in 2006 to 19% in 2010. This was due to complex regulatory and legal frameworks in North America, which led to shifting of the clinical trials market to developing countries such as India and China. This may lead to sluggish growth of clinical trials in the region. Persistence Market Research 2

3. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Countries in Central and Eastern Europe provide abundant opportunities to life science companies for clinical development. According to Oracle Corporation – the percentage of clinical trials conducted in Western Europe has decreased from 25% to 19% and in Eastern Europe; the percentage has increased from 10% to 13% during 2006-2010. However, Asia has become one of the fastest-growing markets for pharmaceutical products. Improved industry regulatory laws and patent expiration laws in various countries such as Japan, China, and India, have led to the expansion of the clinical trials market in Asia. Cost of conducting clinical trials in Asia is lower compared to that in Europe and the U.S. Oracle Corporation, Medidata Solutions, PAREXEL International Corporation, BioClinica, and OmniComm Systems are some of the major players of e-clinical solution software market. The e-clinical solution software market is segmented as follows: By product  Clinical Data Management  Clinical Trial Management System  Electronic Clinical Outcome Assessment Solution  Randomization and Trial Supply Management  Safety Solution By mode of delivery  Web based e-clinical solution software  Licensed Enterprise e-clinical solution software  Cloud based e-clinical solution software Persistence Market Research 3

4. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 By end user  Pharmaceutical  Clinical Research Organizations  Healthcare Providers By geography  North America  U.S Europe  Germany  France  U.K.  Italy  Spain  Poland  Russia Asia  China  South Korea  Taiwan  India  Rest of the World (Row) Persistence Market Research 4

5. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Persistence Market Research 5

6. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Market History: E-clinical solution is software that helps researchers to analyze new ways to manage and analyze clinical data. Globally, the e-clinical solution software market is witnessing significant growth due to increasing clinical trials and R&D investments in pharmaceuticals and life science. Prevalence of diseases such as AIDS, diabetics and cancer are increasing in different regions of the world. It has resulted in an increase in pipeline drugs, which require clinical trials before getting approved. Various lifestyle associated diseases and genetic disorders in the Middle East and North African countries have also enhanced clinical trials in the respective regions. In addition, the pharmaceutical industry is facing immense pressure to reduce the time consumed during clinical trials and to raise the productivity of drugs. Presence of various end users such as pharmaceuticals, clinical research organizations (CRO) and healthcare providers has increased the acceptance of e-clinical solution software. However, unavailability of high-speed internet facility in remote areas negatively impacts the growth of the e-clinical solution software market. The global e-clinical solution software market is estimated at USD 3,005 million in 2014. It is likely to grow at a CAGR of 13.8% from 2014 to 2020 to reach USD 6,515.3 million in 2020. North America is the largest market for the global e-clinical software solution market. Web based e-clinical software solution is the largest mode of delivery and the pharmaceutical industry is the largest end user of e-clinical solution software. In terms of growth, Asia is the fastest growing region, cloud based e-clinical solution software is the fastest growing mode of delivery and CROs are the fastest growing end users of e-clinical solution software. North America is estimated at USD 1,773.9 million in 2014 and is expected to reach USD 3,622.5 million in 2020, growing at a CAGR of 12.6% from 2014 to 2020. The global randomization and trial supply management in e-clinical solution software market is estimated at USD 231.1 million in 2014 and is expected to reach USD 416.5 million in 2020, growing at a CAGR of 9.2% from 2014 to 2020. Persistence Market Research 6

7. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Table of Content Table of Content Chapter 1 Preface 12 1.1 Report Description 12 1.2 Research Methodology 13 1.3 Assumptions 13 Chapter 2 Market Synopsis 14 Chapter 3 Porter’s Five Forces Analysis 16 3.1 Bargaining Power of Suppliers 16 3.2 Bargaining Power of Buyers 17 3.3 Threat of New Entrants 17 3.4 Threat of Substitutes 17 3.5 Intensity of Rivalry 17 Persistence Market Research 7

8. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Chapter 4 Industry Overview 18 4.1 Market Definition 18 4.2 Market Drivers 20 4.2.1 Increasing number of clinical trials 21 4.2.2 Rising spending on clinical research and development in the pharmaceutical industry 22 4.2.3 Growing clinical trial outsourcing 23 4.2.4 Rising need for improved data standardization and reducing the time consumed during clinical trial process 23 4.3 Impact Analysis of Market Drivers 24 4.4 Market Restraints 25 4.4.1 High costs of implementation and lack of skilled manpower 25 4.4.2 Lack of high-speed broadband facilities and IT professionals in remote areas 25 4.4.3 Long approval times for clinical trials 26 4.5 Impact Analysis of Market Restraints 27 4.6 Market Trends 27 4.6.1 Rising number of collaborations and partnerships 27 4.6.2 Increasing number of mergers and acquisitions 28 Chapter 5 Global Market Size and Forecast 30 Chapter 6 Market Size and Forecast by Mode of Delivery 38 6.1 Web-based e-clinical solution software 38 6.2 Licensed Enterprise e-clinical solution software 40 6.3 Cloud-based e-clinical solution software 42 Chapter 7 Market Size and Forecast by Product 45 7.1 Clinical Data Management 45 7.2 Clinical Trial Management System 47 7.3 Electronic Clinical Outcome Assessment Solution 49 7.4 Randomization and Trial Supply Management 51 7.5 Safety Solution 53 Persistence Market Research 8

9. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Chapter 8 Market Size and Forecast by End User 56 8.1 Pharmaceutical 56 8.2 Clinical Research Organization 58 8.3 Healthcare Providers 60 Chapter 9 Market Size and Forecast by Geography 63 9.1 North America 63 9.1.1 U.S. 65 9.2 Europe 68 9.2.1 Germany 71 9.2.2 France 74 9.2.3 Poland 78 9.3 Asia 81 9.3.1 China 85 9.3.2 South Korea 88 9.4 Rest of the World 92 Chapter 10 Competitive Scenario 93 10.1 Competitive Benchmarking 93 Chapter 11 Company Profiles 95 11.1 Oracle Corporation 95 11.1.1 Company Overview 95 11.1.2 Products and Services 95 11.1.3 Financial Performance 96 11.1.4 Recent Developments 96 11.2 Merge Healthcare Incorporated 98 11.2.1 Company Overview 98 11.2.2 Products and Services 98 11.2.3 Financial Performance 99 11.2.4 Recent Developments 99 Persistence Market Research 9

10. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 11.3 Medidata Solutions Inc. 101 11.3.1 Company Overview 101 11.3.2 Products and Services 101 11.3.3 Financial Performance 102 11.3.4 Recent Developments 102 11.4 PAREXEL International Corporation 105 11.4.1 Company Overview 105 11.4.2 Products and Services 105 11.4.3 Financial Performance 105 11.4.4 Recent Developments 106 11.5 BioClinica 107 11.5.1 Company Overview 107 11.5.2 Products and Services 107 11.5.3 Financial Performance 107 11.5.4 Recent Developments 108 11.6 ERT 110 11.6.1 Company Overview 110 11.6.2 Products and Services 110 11.6.3 Financial Performance 110 11.6.4 Recent Developments 111 11.7 OmniComm Systems Inc. 112 11.7.1 Company Overview 112 11.7.2 Products and Services 112 11.7.3 Financial Performance 112 11.7.4 Recent Developments 113 11.8 PHT Corporation 116 11.8.1 Company Overview 116 11.8.2 Products and Services 116 11.8.3 Financial Performance 116 11.8.4 Recent Developments 117 11.9 DATATRAK International Inc. 118 11.9.1 Company Overview 118 11.9.2 Products and Services 118 11.9.3 Financial Performance 119 11.9.4 Recent Developments 119 Persistence Market Research 10

11. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 11.10 CRF Health Inc. 121 11.10.1 Company Overview 121 11.10.2 Products and Services 121 11.10.3 Financial Performance 121 11.10.4 Recent Developments 122 List of Tables TABLE 1 Market Snapshot: E-clinical Solution Software Market (2014 & 2020) 14 TABLE 2 Clinical trials conducted in different countries by December 2011 and May 2014 21 TABLE 3 R&D investment in pharmaceutical industry, by country (US$ Mn) in 2010 and 2011 22 TABLE 4 Drivers for e-clinical solution software market: Impact analysis 24 TABLE 5 Estimated average timelines for clinical trial approval in various countries 26 TABLE 6 Restraints for e-clinical solution software market: Impact analysis 27 TABLE 7 Major major collaborations and partnerships by e-clinical solution software companies (January 2011-May 2014) 28 TABLE 8 Major major mergers and acquisitions in e-clinical solution software market (January 2011- May 2014) 29 TABLE 9 Global e-clinical solution software market size by region, 2009–2013 (US$ Mn) 31 TABLE 10 Global e-clinical solution software market size by region, 2014–2020 (US$ Mn) 31 TABLE 11 Global e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 32 TABLE 12 Global e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 33 TABLE 13 Global e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 34 TABLE 14 Global e-clinical solution software market size by end user 2014–2020 (US$ Mn) 35 TABLE 15 Global e-clinical solution software market size by product, 2009–2013 (US$ Mn) 36 TABLE 16 Global e-clinical solution software market size by product, 2014–2020 (US$ Mn) 36 TABLE 17 Web-based e-clinical solution software market size by region, 2009–2013 (US$ Mn) 39 TABLE 18 Web-based e-clinical solution software market size by region, 2014–2020 (US$ Mn) 39 TABLE 19 Licensed Enterprise e-clinical solution software market size by region, 2009–2013 (US$ Mn) 41 Persistence Market Research 11

12. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 TABLE 20 Licensed Enterprise e-clinical solution software market size by region, 2014–2020 (US$ Mn) 41 TABLE 21 Cloud based e-clinical solution software market size by region, 2009–2013 (US$ Mn) 43 TABLE 22 Cloud-based e-clinical software solution market size by region, 2014–2020 (US$ Mn) 43 TABLE 23 Clinical data management in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 46 TABLE 24 Clinical data management in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 46 TABLE 25 Clinical trial management system in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 48 TABLE 26 Clinical trial management system in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 48 TABLE 27 Electronic clinical outcome assessment solution in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 50 TABLE 28 Electronic clinical outcome assessment solution in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 51 TABLE 29 Randomization and trial supply management in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 52 TABLE 30 Randomization and trial supply management in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 53 TABLE 31 Safety solution in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 54 TABLE 32 Safety solution in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 55 TABLE 33 Pharmaceutical industry in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 57 TABLE 34 Pharmaceutical industry in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 57 TABLE 35 Clinical research organization in e-clinical solution software market size by region, 2009–2013 (US$ Mn) 59 TABLE 36 Clinical research organization in e-clinical solution software market size by region, 2014–2020 (US$ Mn) 59 Persistence Market Research 12

13. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 TABLE 37 Healthcare providers in e-clinical solution software market size by region, 2009– 2013 (US$ Mn) 61 TABLE 38 Healthcare providers in e-clinical solution software market size by region, 2014– 2020 (US$ Mn) 61 TABLE 39 North America e-clinical solution software market size by region, 2009–2013 (US$ Mn) 64 TABLE 40 North America e-clinical solution software market size by region, 2014–2020 (US$ Mn) 64 TABLE 41 U.S. e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 65 TABLE 42 U.S. e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 66 TABLE 43 U.S. e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 67 TABLE 44 U.S. e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 68 TABLE 45 Europe e-clinical solution software market size by region, 2009–2013 (US$ Mn) 69 TABLE 46 Europe e-clinical solution software market size by region, 2014–2020 (US$ Mn) 70 TABLE 47 Germany e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 72 TABLE 48 Germany e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 72 TABLE 49 Germany e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 73 TABLE 50 Germany e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 74 TABLE 51 France e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 75 TABLE 52 France e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 76 TABLE 53 France e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 77 TABLE 54 France e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 77 TABLE 55 Poland e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 78 Persistence Market Research 13

14. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 TABLE 56 Poland e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 79 TABLE 57 Poland e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 80 TABLE 58 Poland e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 81 TABLE 59 Asia e-clinical solution software market size by region, 2009–2013 (US$ Mn) 83 TABLE 60 Asia e-clinical solution software market size by region, 2014–2020 (US$ Mn) 83 TABLE 61 China e-clinical solution software market size by mode of delivery, 2009–2013 (US$ Mn) 86 TABLE 62 China e-clinical solution software market size by mode of delivery, 2014–2020 (US$ Mn) 86 TABLE 63 China e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 87 TABLE 64 China e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 88 TABLE 65 South Korea e-clinical solution software market size by mode of delivery, 2009– 2013 (US$ Mn) 89 TABLE 66 South Korea e-clinical solution software market size by mode of delivery, 2014– 2020 (US$ Mn) 90 TABLE 67 South Korea e-clinical solution software market size by end user, 2009–2013 (US$ Mn) 91 TABLE 68 South Korea e-clinical solution software market size by end user, 2014–2020 (US$ Mn) 91 TABLE 69 MajorMajor Oracle Corporation categories and products 95 TABLE 70 Major Merge Healthcare categories and products 98 TABLE 71 Major Medidata Solutions products and applications 101 TABLE 72 Major PAREXEL International Corporation categories, products and services 105 TABLE 73 Major BioClinica categories and products 107 TABLE 74 Major ERT categories and products 110 TABLE 75 Major OmniComm Systems products and application 112 TABLE 76 Major PHT Corporation categories and products 116 TABLE 77 Major DATATRAK International products 118 TABLE 78 Major CRF Health categories, products and services 121 List of Figures FIG. 1 E-clinical solution software market: Porter’s five forces analysis 16 FIG. 2 Major major technologies in e-clinical solution software 19 Persistence Market Research 14

15. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 FIG. 3 Total e-clinical solution 20 FIG. 4 Global e-clinical solution software market by region, 2013 (% share) 30 FIG. 5 Global e-clinical solution software market, by mode of delivery 2013 (% share) 32 FIG. 6 Global e-clinical solution software market, by end user 2013 (% share) 34 FIG. 7 Global e-clinical solution software market, by product 2013 (% share) 35 FIG. 8 Web based e-clinical solution software market, by region 2013 (% share) 38 FIG. 9 Global e-clinical solution software market, by region 2013 (% share) 40 FIG. 10 Global e-clinical software solution market, by region 2013 (% share) 42 FIG. 11 Clinical data management in e-clinical solution software market, by region, 2013 (% share) 45 FIG. 12 Clinical trial management system in e-clinical solution software market, by region, 2013 (% share) 47 FIG. 13 Electronic clinical outcome assessment solution in e-clinical solution software market, by region, 2013 (% share) 50 FIG. 14 Randomization and trial supply management in e-clinical solution software market, by region, 2013 (% share) 52 FIG. 15 Safety solution in e-clinical solution software market, by region, 2013 (% share) 54 FIG. 16 Pharmaceutical industry in e-clinical solution software market, by region, 2013 (% share) 56 FIG. 17 Clinical research organization in e-clinical solution software market, by region, 2013 (% share) 58 FIG. 18 Healthcare providers in e-clinical solution software market, by region, 2013 (% share) 60 FIG. 19 North America e-clinical solution software market, by region, 2013 (% share) 63 FIG. 20 U.S. e-clinical solution software market, by mode of delivery, 2013 (% share) 65 FIG. 21 U.S. e-clinical solution software market, by end user, 2013 (% share) 67 FIG. 22 Europe e-clinical solution software market, by region, 2013 (% share) 69 FIG. 23 Germanyy e-clinical solution software market, by mode of delivery, 2013 (% share) 71 FIG. 24 Germanyy e-clinical solution software market, by end user, 2013 (% share) 73 FIG. 25 France e-clinical solution software market, by mode of delivery, 2013 (% share) 75 FIG. 26 France e-clinical solution software market, by end user, 2013 (% share) 76 FIG. 27 Poland e-clinical solution software market, by mode of delivery, 2013 (% share) 78 FIG. 28 Poland e-clinical solution software market, by end user, 2013 (% share) 80 FIG. 29 Asia e-clinical solution software market, by region, 2013 (% share) 82 Persistence Market Research 15

16. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 FIG. 30 China e-clinical solution software market, by mode of delivery, 2013 (% share) 85 FIG. 31 China e-clinical solution software market, by end user, 2013 (% share) 87 FIG. 32 South Korea e-clinical solution software market, by mode of delivery, 2013 (% share) 89 FIG. 33 South Korea e-clinical solution software market, by end user, 2013 (% share) 90 FIG. 34 Competitive benchmarking 93 FIG. 35 Oracle Corporation total revenue and net income 2011–2013 (US$ Mn) 96 FIG. 36 Merge Healthcare net sales and net income 2011–2013 (US$ Mn) 99 FIG. 37 Medidata Solutions total revenue and net income 2011–2013 (US$ Mn) 102 FIG. 38 PAREXEL International Corporation total service revenue and net income 2011–2013 (US$ Mn) 106 FIG. 39 BioClinica total revenue and net income 2010-2012 (US$ Mn) 108 FIG. 40 OmniComm Systems total revenue and net income 2011–2013 (US$ Mn) 113 FIG. 41 DATATRAK International revenue and net income 2011–2013 (US$ Mn) 119 About Us: Persistence Market Research is a global market research firm specializing- syndicated research, custom research, and consulting services. At Persistence Market Research (PMR), we are in the business of accelerating your business. As a full- service market research firm, we stand committed to bringing more accuracy and speed to your business decisions. From ready-to-purchase market research reports to customized global research solutions, our engagement models are highly flexible without compromising on our deep-seated research values. Briefly stated, our mission is to give you access to forecasts and trends analyses that put you on the path to profitability. PMR’s Services Go Beyond Gleaning Data Most enterprises believe that IT and databases are enough to make an accurate decision. While we do not dispute that, consider this: How long does it take to make an accurate and strategic million-dollar decision? We strive to deliver both even with demanding deadlines. Persistence Market Research 16

17. Global Market Study on E-clinical Solution Software: Asia to Witness Highest Growth by 2020 Contact Us: Addie Thomes 305 Broadway 7th Floor, New York City, NY 10007, United States, USA - Canada Toll Free: 800-961-0353 Email: sales@persistencemarketresearch.com Web: http://www.persistencemarketresearch.com Persistence Market Research 17