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LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D. 1.932 / xhjkwon@hotmail

BIOINFORMATICS. LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D. 1.932 / xhjkwon@hotmail.com. “BIOINFORMATICS”?. BIO INFORMATICS. BIOLOGY + INFORMATICS The science of information .

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LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D. 1.932 / xhjkwon@hotmail

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  1. BIOINFORMATICS LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D.1.932 / xhjkwon@hotmail.com

  2. “BIOINFORMATICS”?

  3. BIOINFORMATICS BIOLOGY + INFORMATICS The science of information. computer science, human-computer interaction, information science, information technology, algorithms & mathematics

  4. Molecular Biology as an Information Science “Transfer of sequential information”

  5. Information flow in Biological System

  6. Biology & Computer science? Huge amount of Biological Datahave to be stored, analyzed, and retrieved-tasks that are managed with computers.

  7. What is Bioinformatics? Interface of Biology and Computers • The application of computer-based technique in the biological sciences. • The use of computers to collect, analyze, and interpret biological information. • nucleic acid sequence • protein sequences

  8. GENOME TRANSCRIPTOME PROTEOME

  9. DNA sequence ↓ protein sequence ↓ protein structure ↓ protein function ↓ phenotype

  10. “Bioinformatics for Biologists” • The primary goal of bioinformatics is to increase the understanding of biological processes. • Bioinformatics can be seen as a tool that the biologist needs to use. • A set of software tools for molecular sequence analysis! • Computational branch of molecular biology

  11. Searching biological databases • Comparing sequences • Looking at protein structures • Asking biological and biomedical questions with a computer What Bioinformatics can do for you?

  12. For this course, • Computer • Internet connection • Molecular biology background

  13. Many programs can be used online, via the Internet. • In most instances, the information and software are freely available.

  14. textbooks

  15. http://bioinfo.tmmu.edu.cn/downloads/common/upload/files/BioinformaticsandGenomics(EnglishEdition).pdfhttp://bioinfo.tmmu.edu.cn/downloads/common/upload/files/BioinformaticsandGenomics(EnglishEdition).pdf

  16. http://theory.bio.uu.nl/BPA/tb.pdf

  17. Bioinformatics Portals • NCBI (http://www.ncbi.nlm.nih.gov/) • EBI (http://www.ebi.ac.uk/) • ExPASy(http://www.expasy.org/)

  18. interdisciplinary field that develops and improves upon methods for storing, retrieving, organizing and analyzing biological data. BIOINFORMATICS

  19. Genome Analysis • Sequence Analysis • Phylogenetics • Structure Bioinformatics • Gene Expression • System Biology • Bioimage Informatics BIOINFORMATICS

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