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A karyotype DAS client DAS workshop 2009 10 th March Rafael Jimenez

A karyotype DAS client DAS workshop 2009 10 th March Rafael Jimenez. Introduction. Visualization of genome data in combination with experimental data and genome analysis helps to formulate testable hypothesis. Eukaryotic Genome browsers specialized to represent annotations on ...

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A karyotype DAS client DAS workshop 2009 10 th March Rafael Jimenez

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  1. A karyotype DAS client DAS workshop 2009 10th March Rafael Jimenez

  2. Introduction • Visualization of genome data in combination with experimental data and genome analysis helps to formulate testable hypothesis. • Eukaryotic Genome browsers specialized to represent annotations on ... • Specific chromosomes • Genome regions in one chromosome • Detailed views on genome regions • Eukaryotic genome analysis requires visualization in a higher representation level ... • Full genomic context -> Karyotype

  3. Karyotype DAS client DAS web browser to visualize Eukaryotic genome data at the level of karyotype, chromosome and cytoband. Still a prototype! For more detail views in a lower representation level it interacts with the Ensembl web browser. Karyotype DAS viewer Ensembl Karyotype Chromosome Genome region Detailed view

  4. Implementation Service Oriented Architecture Service broker Publish Find Service Contract ... ... Service consumer Service provider Interact

  5. Implementation Distributed Annotation System DASRegistry Registry Gene Expression Profile Analysis SuiteGPAS Publish Find Provide Karyotype DAS Client Genome Analysis DAS ... ... ... Client Sources Interact CromosomeType Ensembl

  6. 1

  7. 1 Quantitative (score) Genome region Qualitative +/- sources by view Chromosome Karyotype

  8. 2 3

  9. 2.1

  10. 2.2

  11. 2.3

  12. 2.4

  13. 2.5

  14. 3.1 binning:maxbins

  15. 3.2

  16. 3.3

  17. 4

  18. Thank you! Thanks for its support to … Bioinfomatics department … especially for his contribution on this project to … Joaquin Tarraga Thanks to our collaborators … UCT South Africa CBIO, UCT South Africa

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