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Translational And Molecular Cardiovascular Nuclear Imaging. Frank M. Bengel Division of Nuclear Medicine/PET Russell H Morgan Dept. of Radiology The Johns Hopkins University Baltimore, MD. JHU Cardiovascular Nuclear Imaging: Focus on Translational Imaging. Basic Science. Clinical Practice.
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Translational And Molecular Cardiovascular Nuclear Imaging Frank M. Bengel Division of Nuclear Medicine/PETRussell H Morgan Dept. of RadiologyThe Johns Hopkins University Baltimore, MD
JHU Cardiovascular Nuclear Imaging:Focus on Translational Imaging Basic Science Clinical Practice • - New tracers • New technology • Imaging disease biology • Imaging of new therapies • Perfusion SPECT-CT • MUGA • Perfusion PET-CT • Viability PET-CT • CCS & CTA as adjunct
Conventional Noninvasive Imaging Measure Severity(Geometry,Function) Measure Extent(Perfusion, LV Function, Scar) Measure Extent(Coronary Calcium, Plaque Burden) Identify Precursors(Endothelial Dysfunction, Vascular Remodeling) Identify Activity(Plaque Vulnerability) Identify Markers ofProgression(LV Remodeling) Molecular Imaging Guide Therapy(Molecular Intervention) Molecular Imaging & Cardiovascular Disease Myocardial Ischemia / Infarction CoronaryAtherosclerosis Heart Failure