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A) Active P-TEFb complexes. CycK. CDK9. CycT1. CDK9. CycK. CDK9. 55. CycT2a. CycT2b. CycT1. CDK9. CDK9. 55. 55. CDK9. 55. CycT2a. CDK9. LARP7 MEPCE. Hexim1 7SK snRNA. CycT1. CDK9. CycT1. CDK9. LARP7 MEPCE. Hexim2 7SK snRNA. CycT2b. CycT1. CDK9. CDK9. LARP7
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A) Active P-TEFb complexes CycK CDK9 CycT1 CDK9 CycK CDK9 55 CycT2a CycT2b CycT1 CDK9 CDK9 55 55 CDK9 55 CycT2a CDK9 LARP7 MEPCE Hexim1 7SK snRNA CycT1 CDK9 CycT1 CDK9 LARP7 MEPCE Hexim2 7SK snRNA CycT2b CycT1 CDK9 CDK9 LARP7 MEPCE Hexim1 7SK snRNA CycT1 CDK9 55 CycT1 CDK9 55 LARP7 MEPCE Hexim2 7SK snRNA CycT1 CDK9 55 B) Inactive P-TEFb complexes with CycT1