The ASU Foundation and The Office of Knowledge Enterprise Development present

1. The ASU Foundation and The Office of Knowledge Enterprise Development present

2. W. M. Keck Foundation Workshop Agenda • Welcome & Introductions • ASUF / OKED Relationship • Keck Overview • Keck Cycle • Keck Experience • Q & A

3. W. M. Keck Foundation • Established in 1954 in Los Angeles byWilliam Myron Keck, founder of The SuperiorOil Company • Bold, creative approach to philanthropy for wide benefit to humanity • Pioneering discoveries in science, engineering and medical research • Focus on: basic research solve fundamental scientific problems seek out new ideas, questions and innovations advance body of scientific knowledge, enhance human health

4. W. M. Keck Foundation Funding • Assets (2010) $1B • Funding (2010) $46M • Emergent, catalytic research • Innovative, distinctive, transformative solutions • Demonstrate high-risk/high-reward and push edge of field/ question prevailing paradigm • Outside scope of federal funding agencies • Interdisciplinary collaborations are key • Research grants capped $1M for maximum 5 years

5. Keck Programs and Priorities Science & Engineering Program • Benefit humanity by supporting high-risk/high-impact work of leading researchers • Foster new paradigms, technologies and discoveries that will save lives, provide innovative solutions, and add to our understanding of the world • Grants to major universities and independent research institutions supporting pioneering science and engineering research, development of promising new technologies, and to facilitate purchase of advanced instruments where such instruments would further research ideas • Representative Grants

6. Keck Programs and Priorities Medical Research Program • Advance the frontiers of medicine to benefit humanity by supporting high-risk/high-impact projects that are distinctive and novel in approach, cutting edge and transformational • Grants to major universities and independent research institutions supporting pioneering biological research, development of promising new technologies, and to facilitate purchase of advanced instruments where such instruments would further research ideas • Research projects should focus on basic research and not be clinical in nature. Medical research projects conducted in hospitals are not eligible. • Representative Grants

7. ASU and W.M. Keck Foundation • Strengthened institutional visibility and relationship with Keck leadership • Total Giving to ASU: $4,900,000 Frameshifts as Cancer Vaccine Targetsthrough the School of Life Sciences, College of Liberal Arts and Sciences, S. Johnston ($1,200,000; 2007)Live-Cell Computed Tomography Instrumentation Development, ASU Biodesign Institute, D. Meldrum ($1,000,000; 2010) A Self-Assembled Nanomechanical System (NMES) for Molecular Detections, ASU Biodesign Institute, N.J. Tao ($1,000,000; 2011) • Pending Activity 1 Pending Phase II application ($1,000,000, 2011) 2 Pending Phase I applications ($1,000,000 each, 2012) December 2012 Concepts – Open ($1,000,000)

8. The Keck Cycle Reporting

9. The Keck Timeline • 2 funding cycles per year: December & June • 1 application per program, per cycle • December cycle currently open

10. Pre-application Process Concept Paper • Use Keck priorities as guidelines • Focus on the unique aspects that relate to transformative, high-impact/high-risk research, including methodologies & resulting knowledge that has the potential to revolutionize the field • Justification: Make the case for Keck support based on your experience with public funding/other agencies.Be specific. • Space is limited. Use focused, precise language written for a “well-educated lay audience.” Pre-application Consultation • Clear, focused and precise concept paper that can be well-conveyed to Keck officials by OFR and OKED

11. Phase I Application

12. Post – Submission • Review for completeness and adherence to requirements • Reviewed by Keck committees – Science and Engineering or Medical Research • Approximately six weeks between submission and notification of invitation to submit full proposal • Official notification to ASU President’s Office and the ASU Foundation Keck Liaison • Faculty notification and invitation to Phase II consultation with OFR

13. Phase II Applications • One month turn around • All about the science (and Keck priorities!) • Transformative, unique, high-risk/high-impact • Interdisciplinary teams highly desirable • External collaborators a bonus • Collaborator support letters required • Post submission site visit

14. Discussion • Thoughts & Observations from Prior Keck Participants • Questions

15. Resources • W.M. Keck Foundation: www.wmkeck.org • Foundation Relations (OFR) • Meghan.Mckendry@asu.edu • Vicki.Svoboda@asu.edu • W.M. Keck Foundation Research Forum Packet • PPT Presentation • Concept Paper Template • Keck Priorities • Timeline