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Our New Organelle Design

Nitrosolvo, a new organelle found in red blood cells, works to dissolve nitrogen bubbles that cause decompression sickness, helping prevent dangerous symptoms during pressure changes underwater or in planes. This innovative structure engulfs nitrogen bubbles, releases gas, and interacts with cell components for efficient gas diffusion. While beneficial in managing pressure-related health risks, Nitrosolvo may have drawbacks related to nitric oxide levels. Inspired by medical cases and the need for natural pressure adaptation, this project explores the role and potential impact of this unique organelle.

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Our New Organelle Design

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  1. Our New Organelle Design

  2. Nitrosolvo • Nitrosolvo means “to dissolve nitrogen” • Name has Latin origins • Organelle is located in red blood cells • Red blood cells are located in the bloodstream

  3. Decompression Sickness • Your lungs inhale a certain amount of nitrogen in the air • When you are under water the nitrogen in your lungs becomes more dense because there is more pressure • The body seeks equilibrium with your lungs by diffusing nitrogen into muscle tissue and bones

  4. When you ascend towards the surface of the water the pressure of the nitrogen in your lungs decreases and the pressure of nitrogen in your blood and tissues decreases • When you ascend too quickly nitrogen will rush out of your blood in bubble form, causing decompression sickness • Symptoms include: headache, fatigue, rash, joint pain, paralysis, tingling, unconsciousness, or death

  5. Nitrosolvo’s Structure

  6. Nitrosolvo’s Functions • Nitrosolvo engulfs nitrogen bubbles • Enzymes eat nitrogen bubbles • Enzymes then release gas • The gas dissolves into bloodstream

  7. Nitrosolvo’s Interactions • cell membrane: the organelle is stationed in the cell membrane • lysosomes: the waste from the outside of the bubble is transported to the lysosome • mitochondrion: the organelle gets its energy from the mitochondrion because it has to change shape to let in the nitrogen bubbles.

  8. Positive Effects • Helps those who experience pressure changes • Decreases risk of death by decompression sickness or “the bends” • Mainly effects divers, sperm whales, and those in airplanes that lose cabin pressure

  9. Negative Effects • Nitrosolvo may allow a smaller amount of nitric oxide • Nitric oxide helps muscles relax and increase blood flow

  10. Project Inspiration • In one episode of House MD in which a man gets “The Bends” from Scuba Diving, surfacing too quickly, and then boarding a plane. • We wanted to learn about decompression sickness because it is not well known and the topic of pressure arose in class • After discussing the episode in class we decided to create an organelle that would allow the body to naturally adapt to changes in pressure

  11. Works Cited • Lynch, Tim.”Freedict onldict”.1986.3 Jan. 09. <http://www.freedict.com/onldict/onldict.phb> • Adam, John.”Carbon”.1985.3 Jan 2009. <http://www.dailymail.co.uk/news/article_1049148/passenger_hell_jet_plunges_26_oooft_minutes_drop_carbon_pressure.html< • Thompson, John.”News Health”.1996.3 Jan 2009. <http://news.bbc.co.uk/2/hi/health/1110678.stm> • “Duke Health”. Duke Health Club.1984.Duke University.3 Jan. 2009. <http://www.dukehealth.org/healthlibrary/healtharticles/diving_deep_flying_high> • “Live Science”2000.3 Jan 2009. <http://www.livescience.com/animals/whale_bends_041224.html> • The Cardiovascular System - Design, Working, Ailments, Taking care. 2007. Free Health Encyclopedia. 5 Jan. 2009 <http://www.faqs.org/health/Body-by-Design-V1/The-Cardiovascular- System.html>. • "Decompression sickness." NetDoctor.co.uk - The UK's leading independent health website. 4 Jan. 2005. NetDoctor. 05 Jan. 2009 <http://www.netdoctor.co.uk/travel/diseases/decompression_sickness.htm>.

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