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ROS/NO/O2 1a. Introduction: Background. ENDOTHELIAL FUNCTION OF SUBDERMAL MICROVESSELS, PLASMA ADMA AND ROS MARKERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 1 OR EARLY ESSENTIAL HYPERTENSION. Dan Wang, M.D., Ph.D. Christopher Wilcox, M.D., Ph.D. Sven Strangaard , Ph.D.
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ENDOTHELIAL FUNCTION OF SUBDERMAL MICROVESSELS, PLASMA ADMA AND ROS MARKERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 1 OR EARLY ESSENTIAL HYPERTENSION • Dan Wang, M.D., Ph.D. • Christopher Wilcox, M.D., Ph.D. • Sven Strangaard, Ph.D. • ShakilAslam, M.D.
CONCLUSIONS • Humans with essential hypertension or CKD-1 have: • reduced microvascular EDRF and NOS • increased circulating ADMA • oxidative stress