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Supramolecular Encapsulation of Bio-Inspired Models by Cucurbiturils: Progress Report

Supramolecular Encapsulation of Bio-Inspired Models by Cucurbiturils: Progress Report. Cátia Parente Carvalho Uwe Pischel (UHU) José Paulo da Silva (UALG). SUPRABIOENCAPS. Aim:. Development of new fluorescent molecules for marking of nanocapsules . Guest. Host. Supramolecular Complex.

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Supramolecular Encapsulation of Bio-Inspired Models by Cucurbiturils: Progress Report

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  1. Supramolecular Encapsulation of Bio-Inspired Models by Cucurbiturils: Progress Report Cátia Parente Carvalho Uwe Pischel (UHU) José Paulo da Silva (UALG) SUPRABIOENCAPS

  2. Aim: • Development of new fluorescent molecules for marking of nanocapsules Guest Host Supramolecular Complex

  3. A novel fluorophore-anchor dye has been designed and characterised with respect to its ability to form supramolecular host-guest complexes with cucurbit[6]uril and cucurbit[7]uril . CB[n] Complex formation between the Aminonaphthalimide-Putrescine•Cucurbit[n]uril Aminonaphthalimide-Putrescine

  4. Complex formation: • Absorption spectroscopy • Fluorescence spectroscopy • Mass spectrometry • RMN

  5. Sensor for Biogenic Amines Supramolecular Complex Amine (Guest 2) Guest 1 Supramolecular Complex 2 Change of Fluorescence

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