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Viability (% control)

A. DAOY wt. Etoposide µg/ml. Cisplatin µg/ml. c-MYC siRNA. c-MYC siRNA. Control siRNA. Control siRNA. 120. 120. 100. 100. 80. 80. 60. 60. 40. 40. 20. 20. 0. 0. 120. 100. 80. Viability (% control). 60. 40. 0.6846 [0.5360 - 0.8744]. 20. 0.7464 [0.6653 to 0.8372].

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Viability (% control)

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  1. A DAOY wt Etoposide µg/ml Cisplatin µg/ml c-MYC siRNA c-MYC siRNA Control siRNA Control siRNA 120 120 100 100 80 80 60 60 40 40 20 20 0 0 120 100 80 Viability (% control) 60 40 0.6846 [0.5360 - 0.8744] 20 0.7464 [0.6653 to 0.8372] 0 0 0.08 0.15 0.30 0.60 1.20 2.40 4.80 0.04 DAOY V11 D341 120 100 0.5166 [0.3348 - 0.7973] 80 Viability (% control) 0.2558 [0.1048 - 0.6245] Viability (% control) 60 40 0.4631 [0.4045 to 0.5302] 20 0.4929 [0.4567 to 0.5320] 0 0 5 0 40 10 20 0.16 0.31 0.63 1.25 2.50 4.80 0.04 0.08 0.15 0.30 0.60 1.20 2.40 DAOY M2 D425 120 100 80 Viability (% control) Viability (% control) 60 40 0.7143 [0.5789 - 0.8813] 3.195 [2.902 - 3.517] 20 0.182 [0.09133 - 0.3642] 1.854 [1.390 - 2.474] 0 0 5 0 10 20 40 0.16 0.31 0.63 1.25 2.50 0.04 0.08 0.15 0.30 0.60 1.20 2.40 4.80 B DAOY wt 120 100 80 Viability (% control) 60 40 1.225 [1.014 - 1.480] 20 0.259 [0.2043 - 0.3290] 0 5 0 0.04 0.08 0.16 0.31 0.63 1.25 2.50 DAOY V11 D341 120 120 100 100 80 80 Viability (% control) Viability (% control) 60 60 40 40 3.184 [2.511 - 4.037] 0.112 [0.1016 - 0.1237] 20 20 0.516 [0.3769 - 0.7063] 0.058 [0.04713 - 0.07204] 0 0 5 0 0 0.04 0.08 0.16 0.31 0.63 1.25 2.50 1.25 0.01 0.02 0.31 0.63 0.04 0.08 0.16 DAOY M2 D425 120 120 100 100 80 80 Viability (% control) Viability (% control) 60 60 40 40 2.627 [1.669 - 4.134] 3.80 [1.947 - 8.415] 20 20 0.182 [0.09133 - 0.3642] 2.03 [1.091 - 3.770] 0 0 0 5 0 5 10 20 40 0.04 0.08 0.16 0.31 0.63 1.25 2.50 0.16 0.31 0.63 1.25 2.50

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