Immunization Update 2007 Satellite Broadcast/Webcast August 9, 2007 Vaccine Briefs Segment

Immunization Update 2007 Satellite Broadcast/Webcast August 9, 2007 Vaccine Briefs Segment Graphics subject to change. This material in the public domain.

Human Papillomavirus (HPV) Vaccine Schedule • Females 9 through 26 years of age • Routine schedule is 0, 2, and 6 months • Minimum intervals: • 4 weeks between doses 1 and 2 • 12 weeks between doses 2 and 3 Source: MMWR 2007;56(No. RR-2)

HPV Vaccination ACIP Recommendations • Routine vaccination of females 11-12 years of age with three doses of quadrivalent HPV vaccine • The vaccination series can be started as young as 9 years of age at the clinician’s discretion Source: MMWR 2007;56(No. RR-2)

HPV Vaccination ACIP Recommendations • Vaccination is recommended for females 13 through 26 years of age not previously vaccinated • Vaccine should be administered before onset of sexual activity, if possible • Females who are sexually active should be vaccinated Source: MMWR 2007;56(No. RR-2)

HPV VaccineSpecial Situations • Females 26 years of age or younger with equivocal or abnormal Pap test, positive HPV DNA, or genital warts may be vaccinated • Vaccine will have no effect on existing disease or infection Source: MMWR 2007;56(No. RR-2)

HPV VaccineSpecial Situations • Females 26 years of age or younger who are lactating and breastfeeding, or are immuno-compromised may be vaccinated • NOT recommended for pregnant women Source: MMWR 2007;56(No. RR-2)

HPV Vaccine • HPV vaccine is not approved for women older than 26 years or males • Efficacy data is not yet available for these groups • ACIP does NOT recommend off-label in either women older than 26 years or in males

General Recommendationson Immunization, 2006 • Vaccine administration • Vaccine storage and handling • Altered immunocompetence • Special situations • allergy to vaccine components • pregnancy • vaccines received outside the U.S. • persons with bleeding disorders

General Recommendationson Immunization, 2006 • New or expanded tables • minimum intervals and ages • contraindications and precautions • dose and route of administration • needle length and injection sites • vaccine storage temperatures • vaccine recommendations for persons with immune deficiencies

Twinrix “Accelerated” Schedule • Doses at 0, 7, 21-30 days and a booster dose at 12 months • Approved only for persons 18 years and older • The first THREE doses of the newly- licensed Twinrix schedule provide equivalent protection to • the first dose in the standard, single antigen adult hepatitis A vaccine series • the first two doses in the standard adult hepatitis B vaccine series

Vaccine Information Statements • Every healthcare provider, public or private, who administers a vaccine covered by the National Childhood Vaccine Injury Act is required by law to provide a copy of the most current VIS with EACH DOSE of vaccine

Vaccine Information Statements • Not required by Federal law to obtain a signature • Must note in each patient’s permanent medical record or permanent office file: • date printed on the VIS • date the VIS is given to the vaccine recipient, or their legal representative

Vaccine Information StatementsNew or Revised Since August 2006 • New • Human papillomavirus • Zoster • Revised • DTaP • Hepatitis B • Varicella • Meningococcal • Influenza (TIV and LAIV)

CDC Vaccines and ImmunizationContact Information • Hotline (800) CDC-INFO • Email nipinfo@cdc.gov • Website www.cdc.gov/nip • Broadcast Updates and Resources Web Page www.cdc.gov/vaccines/ed/broadcasts.htm

Immunization Update 2007 Satellite Broadcast/Webcast August 9, 2007 Vaccine Briefs Segment