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DENT 514: Research Methods. Masahiro Heima, DDS, PhD. Lecture 5-6: Step by Step. Step by Step . Have a question. Do a systematic searching for articles for your question. Did you find the answer?. Yes!. No, I couldn’t. Get a team including a mentor and co-investigators.
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DENT 514: Research Methods Masahiro Heima, DDS, PhD
Step by Step Have a question Do a systematic searching for articles for your question Did you find the answer? Yes! No, I couldn’t. Get a team including a mentor and co-investigators Congratulations! Brainstorming
Justify your research project (e.g. “Based on the current knowledge, we know _____. However, there is a limitation of information about _____.”) State objectives/hypotheses of your research Can you state your hypotheses using numbers (variables)? Use objective variable Yes No, I couldn’t It is objective! It is NOT objective!
State hypotheses and null hypotheses List variables to test your hypotheses and possible confounders or factors which influence your outcome State your target population Do you have enough financial support for your research? No Yes Can you use “convenient” source/ volunteers? Yes No Get money
Do you have access to your entire population? Yes No Are you able to collect your data from your entire population? Yes No Decide sampling method Calculate sample size
Is there the standardized research methodology? Yes No Decide research design in order to minimize biases and control confounders Follow the method Generate a proposal State the inclusion and exclusion criteria of subject
List risks (adverse effects) and benefits Are the risk more than the minimum risk?: Minimal risk is the probability and magnitude of physical or psychological harm that is normally encountered in the daily lives, or in the routine medical, dental, or psychological examination of healthy persons (U.S. Department of Health & Human Services). Yes No Can you change the protocol in order to reduce the risk to the level of “minimum”? Yes No
Change the protocol Cannot change the protocol! Justify the risk Generate statistic plan, e.g. descriptive analysis, comparisons…. for each of your hypothesis Simulate the protocol to find mistakes or problems Obtain departmental and IRB approval as needed
Create a database on a secure place such as password protected computer/server or secure web based program such as RedCap Conduct research Collect data Is original data on paper? Yes, it’s on paper. No, it is on an electronic source.
Is it capable of transferring to the database? No Yes Do double entry Transfer Generate the database Analyze data Interpret results Publish