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SANBI Glossina comparative genomics workshop:

SANBI Glossina comparative genomics workshop:. TDR new strategy and vector research operational plan Yeya T. Touré WHO-TDR (tourey@who.int). Outline of the presentation. TDR new vision and strategy

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SANBI Glossina comparative genomics workshop:

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  1. SANBI Glossina comparative genomics workshop: TDR new strategy and vector research operational plan Yeya T. Touré WHO-TDR (tourey@who.int)

  2. Outline of the presentation • TDR new vision and strategy • Business Line 5: Innovative vector control interventions: Objectives, activities and operational plan

  3. TDR new vision and strategy

  4. TDR was established as a special programme 30 years ago • Mission • To develop new and improved tools for tropical disease control • To strengthen the research capability of disease endemic countries (DECs) • Track record • Supported >10,000 projects; trained >1,500 PhD scientists • Five of 10 tropical diseases targeted for global / regional elimination • Key strengths • UN’s convening power • Location in WHO and links to ministries and control • Partner network and brokering capabilities • Long-standing DEC relationships • Governance structure

  5. TDR Vision and Strategy www.who.int/tdr

  6. TDR Vision To foster: An effective global research effort on infectious diseases of poverty in which disease endemic countries play a pivotal role

  7. Strategic objectives Innovation Interventions Access

  8. Stewardship / Priority Setting

  9. Empowerment through:Training, Institutional Support and Networks Research systems (quality assurance)

  10. Business Line 5: objectives, activities and operational plan

  11. BL 5 strategic objectives Overall objective: To develop and evaluate improved and innovative vector control methods for the prevention of neglected diseases. Specific objectives: • To promote the development and testing of new methods for improving Human African Trypanosomiasis (HAT) vector control and support the generation and exploitation of Glossina genome sequence data • To advance the development and evaluation of new and improved integrated methods for malaria and dengue vector control • To progress the development and evaluation of alternative methods for the prevention of re-infestation and the control of Chagas disease vectors

  12. Building capacity in biosafety, exploitation of vector genome data, training within funded grants Facilitating the Glossina genome sequencing initiative Development and evaluation of improved vector control methods

  13. Consultation meeting defined BL 5 activities and operational framework • HAT (Human African Trypanosomiasis): - Improving bait technology, odour release systems and trapping materials for the enhancement of effectiveness of tsetse fly trapping - Improving the efficacy of HAT vector control programs through evidence-based planning and implementation of control strategies • Genetic modification of malaria and dengue vectors: - Addressing the requirements for deployment of genetic control methods • Malaria: - Developing and evaluating tailored methods for integrated malaria vector control - Characterizing malaria vector resistance to insecticides • Dengue: - Improving methods for targeted and integrated dengue vector control approaches • Chagas disease: - Developing improved methods for the prevention of re-infestation by triatomine bugs - Developing new methods for control of Chagas disease vectors Consultation on a framework for transition from current activities and implementation of the new vector research strategy Geneva, 23-24 April 2007

  14. Objective 1: HAT vector control: Activities, end-products and milestones

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