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Imaging Capacities. The ability to collect imaging data from different sites The ability to share imaging data from different sites The ability to analyze imaging data from different sites The ability to combine images at different scales Types of data Structural imaging Functional imaging
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Imaging Capacities • The ability to collect imaging data from different sites • The ability to share imaging data from different sites • The ability to analyze imaging data from different sites • The ability to combine images at different scales • Types of data • Structural imaging • Functional imaging • Arterial Spin Labeling • Diffusion Weighted imaging • Mouse models
2007 Can MR Data Be Combined Across Sites? 2003 Same subject, same slice, different scanners Every parameter matters…
Multi-site fMRI: 3T scanners BWH Duke MGH Yale
Warping Due to Imaging Gradient Imperfections • Overview • License-free code that unwarps images and decreases intensity variability. • Currently supports GE and Siemens gradient sets. (Working on Philips…)
Application – Cortical Boundaries Siemens GE Same Subject Co-registered CORTICAL ESTIMATES: NO DISTORTION CORRECTION CORTICAL ESTIMATES: DISTORTION CORRECTION Lesson: Head placement is important!
BIRN Covers Entire Data Flow Workflows Workbench Pipeline Data Processing Integrate Database Management Data Acquisition Local DB Remote DB Data Grid Share Discover Visualize Analyze
Mouse BIRN Atlasing Toolkit (MBAT) keyword search & query term search cart move data between workspaces • search workspace search result table hover to show thumbnail image
viewer workspace display data from online DB & local image data and atlases in a single viewer online data from CCDB & GenSat hierarchy viewer- read OBO format
For more information • Frequently Asked Questions wiki • https://xwiki.nbirn.org:8443/bin/view/Function-BIRN/FBIRN_Best_Practices • https://xwiki.nbirn.org:8443/bin/view/Morphometry-BIRN/mBIRN_DTI_protocols • Tools available through the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC, www.nitrc.org) • Agar phantom tools for scanner fMRI quality assurance • Database schema for generic, federated experimental data storage • MBAT • Imaging processing and analysis tools: FIPS, Slicer, Freesurfer, etc. • XML-based Clinical and Experimental Data Exchange (XCEDE) • www.xcede.org