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ICb-1487-I ICb-1595-III ICb-1595-I Pt-1595 Pt-1299 Pt1487 Pt-1078 ICb-1078-III ICb-1078-I

ICb-1487-I ICb-1595-III ICb-1595-I Pt-1595 Pt-1299 Pt1487 Pt-1078 ICb-1078-III ICb-1078-I ICb-1078-V ICb-1299-V ICb-1299-III ICb-1487-III Pt-1572 ICb-1572-III ICb-1572-I ICb-1572-V ICb-1494-I ICb-1197-III ICb-1494-III ICb-1494-V ICb-1197-I Pt-1494 ICb-1299-I ICb-984-III

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ICb-1487-I ICb-1595-III ICb-1595-I Pt-1595 Pt-1299 Pt1487 Pt-1078 ICb-1078-III ICb-1078-I

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  1. ICb-1487-I ICb-1595-III ICb-1595-I Pt-1595 Pt-1299 Pt1487 Pt-1078 ICb-1078-III ICb-1078-I ICb-1078-V ICb-1299-V ICb-1299-III ICb-1487-III Pt-1572 ICb-1572-III ICb-1572-I ICb-1572-V ICb-1494-I ICb-1197-III ICb-1494-III ICb-1494-V ICb-1197-I Pt-1494 ICb-1299-I ICb-984-III ICb-984-V ICb-984-I Pt-1338 ICb-1338-III ICb-1338-I ICb-1140-I ICb-1140-III Pt-1140 ICb-1192III ICb-1192-V ICb-II92-I Pt-1192 Supplemental Figure 3. Heatmap showing the subclassification of patient tumors (Pt) together with their Intracerebellar (ICb) xenograft tumors from passage I (I) to passage V (V) using the molecular classifiers identified by Northcott et al (2010). The dendrogram at the top of the figure shows the grouping of the samples. The length of the legs is indicative of the correlation among the samples. The short the legs, the closer they are. Group D Group C SHH WNT Group C Group D WNT SHH

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