Theme 10 Simulation of a Licensing Negotiation Introduction to the Game (Diagram)

1. Successful Technology Licensing (STL)Train the Trainers ProgramRio de Janeiro, Brazil, March 28 to 31, 2006 Theme 10Simulation of a Licensing NegotiationIntroduction to the Game (Diagram)

2. IP Ownership? Technology Status(Completed or Not) Scope for Nanolin and Nano-Chip License May be different Large Potential Marketfor Nanolin (20 billion US Dollars) Cluster II Cluster I IP Ownershipor Unlimited Exclusivity NEGOTIATION STRATEGY Clinical Trial Costs Clarify Subject Matter(Nanolin and Nano-Chip) Up Front Fee or Lump-Sum Payment for Research Limited Responsibility for Risk BIO MED Cluster III Right to Modify and Improve Cap Royalties Cluster IV Want to Control future Developmentof the Technologies “First line” - assignment of IP rights or Worldwide Exclusivity on Nano chip University Needs Funds forResearch BUSINESS OBJECTIVES Leverage Nano-Chip not finalized “Bottom line” - limited exclusivity Dr. Cruz as Employee of Bio Med NanolinNot Clinically Tested

3. Nee to complete the technologyfor Nanolin and Nano-Chip IP Ownership(University Policy) In-exclusive for Nanochip Large market, potentialnett Cash flow in 5 yrs - 875.5 million U.S. Cluster II Cluster I Cluster III Ready to give exclusive license forNanoline To keep right to modify Up-front feefor research BioMed to payIndemnities NEGOTIATION STRATEGY Need to complete clinical testing Minimum royalties To keep new versions of Nano-Chip Cluster IV Want right on new versions on Nano-Chip BioMed to pay cost of clinical testing UNIVERSITY DO LITORAL Limit Dr. Crus’s BioMed cooperation on consultancy level Dr. Octavio Cruz Mr. Lui Antonio Simon Mr. Raul Barbosa Need funds for research Alternative Financing From Dr. Lattes BUSINESS OBJECTIVES Nanolin Drug with potential huge Market Keep control over use of Nanolin Chip Leverage for University IP Ownership Distribution of Nanolin for public health Nano-chip Universal Testing Tool