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Ch. 22/23 Warm-up

Ch. 22/23 Warm-up. List 5 different pieces of evidence for evolution. (Review) W hat are the 3 ways that sexual reproduction produces genetic diversity? What is 1 thing you are grateful for today?. Ch. 23 Warm-up.

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Ch. 22/23 Warm-up

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  1. Ch. 22/23 Warm-up • List 5 different pieces of evidence for evolution. • (Review) What are the 3 ways that sexual reproduction produces genetic diversity? • What is 1 thing you are grateful for today?

  2. Ch. 23 Warm-up • In a population of 200 mice, 98 are homozygous dominant for brown coat color (BB), 84 are heterozygous (Bb), and 18 are homozygous (bb). • The allele frequencies of this population are: B allele: ___ b allele: ___ • The genotype frequencies are: BB: ___ Bb: ___ bb: ___ • Use the above info to determine the genotype frequencies of the next generation: B (p): ___ b (q): ___ BB (p2): ___ Bb (2pq): ___ bb (q2): ___

  3. The Evolution of Populations Chapter 23

  4. What you must know: • How mutation and sexual reproduction each produce genetic variation. • The conditions for Hardy-Weinberg equilibrium. • How to use the Hardy-Weinburg equation to calculate allelic frequencies and to test whether a population is evolving.

  5. Smallest unit of evolution Microevolution: change in the allele frequencies of a population over generations

  6. Darwin did not know how organisms passed traits to offspring 1866 - Mendel published his paper on genetics Mendelian genetics supports Darwin’s theory  Evolution is based on genetic variation

  7. Sources of Genetic Variation • Point mutations: changes in one base (eg. sickle cell) • Chromosomal mutations: delete, duplicate, disrupt, rearrange  usually harmful • Sexual recombination: contributes to most of genetic variation in a population • Crossing Over (Meiosis – Prophase I) • Independent Assortment of Chromosomes (during meiosis) • Random Fertilization (sperm + egg)

  8. Population genetics: study of how populations change genetically over time Population: group of individuals that live in the same area and interbreed, producing fertile offspring

  9. Gene pool: all of the alleles for all genes in all the members of the population • Diploid species: 2 alleles for a gene (homozygous/heterozygous) • Fixed allele: all members of a population only have 1 allele for a particular trait • The more fixed alleles a population has, the LOWER the species’ diversity

  10. Causes of evolution

  11. Minor Causes of Evolution: #1 - Mutations • Rare, very small changes in allele frequencies #2 - Nonrandom mating • Affect genotypes, but not allele frequencies Major Causes of Evolution: • Natural selection, genetic drift, gene flow (#3-5)

  12. Major Causes of Evolution #3 – Natural Selection • Individuals with variations better suited to environment pass more alleles to next generation

  13. Major Causes of Evolution #4 – Genetic Drift • Small populations have greater chance of fluctuations in allele frequencies from one generation to another • Examples: • Founder Effect • Bottleneck Effect

  14. Genetic Drift

  15. Founder Effect • A few individuals isolated from larger population • Certain alleles under/over represented Polydactyly in Amish population

  16. Bottleneck Effect • Sudden change in environment drastically reduces population size Northern elephant seals hunted nearly to extinction in California

  17. Major Causes of Evolution #5 – Gene Flow • Movement of fertile individuals between populations • Gain/lose alleles • Reduce genetic differences between populations

  18. Hardy-Weinberg Principle Hardy-Weinberg Principle: The allele and genotype frequencies of a population will remain constant from generation to generation …UNLESS they are acted upon by forces other than Mendelian segregation and recombination of alleles Equilibrium= allele and genotype frequencies remain constant

  19. Conditions for Hardy-Weinberg equilibrium • No mutations. • Random mating. • No natural selection. • Extremely large population size. • No gene flow. If at least one of these conditions is NOT met, then the population is EVOLVING!

  20. p + q = 1 Note: 1 – p = q 1 – q = p Allele Frequencies: Gene with 2 alleles : p, q p = frequency of dominant allele (A) q = frequency of recessive allele (a)

  21. p2 + 2pq + q2 = 1 Genotypic Frequencies: • 3 genotypes (AA, Aa, aa) p2 = AA (homozygous dominant) 2pq = Aa (heterozygous) q2 = aa (homozygous recessive)

  22. H-W Equilibrium: • If If p and q are not constant from generation to generation, then the POPULATION IS EVOLVING!

  23. Hardy-weinberg practice problem #1 The scarlet tiger moth has the following genotypes. Calculate the allele and genotype frequencies (%) for a population of 1600 moths. AA = 512 Aa = 788 aa = 300 Allele Frequencies: A (p) = a (q)= Genotypic Frequencies: AA = Aa = aa =

  24. Hardy-weinberg practice problem #1 Find out p and q AA = 512 Aa = 788 aa = 300 if aa = 300 then the frequency of aa = 300/1600 = 0.1875 aa is the same as q2 so q = √0.1875 = 0.433

  25. Hardy-weinberg practice problem #1 Find out p and q AA = 512 Aa = 788 aa = 300 If q = 0.433 then p = 1-q 1-0.433 = 0.567 p= 0.567 q= 0.433

  26. Hardy-weinberg practice problem #1 Find out p and q AA = 512 Aa = 788 aa = 300 p= 0.567 q= 0.433 Genotypic Frequencies: AA is the same as p2 = 0.5672 = 0.3215 Aa is the same as 2pq = 0.4910 aa is the same as q2 = 0.4332 = 0.1875 =

  27. Hardy-weinberg practice problem #1 The previous generation of tiger moths showed an allele frequency of p= 0.7 q= 0.3 What can you say about the population of moths?

  28. How does natural selection bring about adaptive evolution?

  29. Natural selection can alter frequency distribution of heritable traits in 3 ways: • Directional selection • Disruptive (diversifying) selection • Stabilizing selection

  30. Disruptive Selection: eg. small beaks for small seeds; large beaks for large seeds Stabilizing Selection: eg. narrow range of human birth weight Directional Selection: eg. larger black bears survive extreme cold better than small ones

  31. Sexual selection • Form of natural selection – certain individuals more likely to obtain mates • Sexual dimorphism: difference between 2 sexes • Size, color, ornamentation, behavior

  32. Sexual selection • Intrasexual– selection within same sex (eg. M compete with other M) • Intersexual– mate choice (eg. F choose showy M)

  33. Preserving genetic variation • Diploidy: hide recessive alleles that are less favorable • Heterozygote advantage: greater fitness than homozygotes • eg. Sickle cell disease

  34. HHMI Video:Natural Selection in Humans Running Time: 14:03 min

  35. Natural selection cannot fashion perfect organisms. • Selection can act only on existing variations. • Evolution is limited by historical constraints. • Adaptations are often compromises. • Chance, natural selection, and the environment interact.

  36. Sample Problem Define the following examples as directional, disruptive, or stabilizing selection: • Tiger cubs usually weigh 2-3 lbs. at birth • Butterflies in 2 different colors each represent a species distasteful to birds • Brightly colored birds mate more frequently than drab birds of same species • Fossil evidence of horse size increasing over time

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