1 / 6

Liquid Chromatography

Liquid Chromatography. Ulrich Tallarek and Ernst Bayer Institute of Organic Chemistry University of Tübingen Tübingen, Germany Dagmar van Dusschoten and Henk Van As WnmrC. Fluid Flow. moving fluid. “stationary fluid”. overall flow direction of fluid. internal pore. 0.15. 0.10. 0.05.

kevyn-knox
Download Presentation

Liquid Chromatography

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Liquid Chromatography Ulrich Tallarek and Ernst Bayer Institute of Organic Chemistry University of Tübingen Tübingen, Germany Dagmar van Dusschoten and Henk Van As WnmrC

  2. Fluid Flow moving fluid “stationary fluid” overall flow direction of fluid internal pore

  3. 0.15 0.10 0.05 0.00 0.0000 0.0005 0.0010 0.0015 Mass Transfer “stationary” fluid (21%) diffusion within particles Conditions - water flow rate: 8.8 mL/min - observation time: 30 ms moving fluid (79%) dispersion between particles Averaged Propagator [a.u.] Dynamic Displacements [m]

  4. Axial dispersion Pixel number NMR Image of Column

  5. Transport Parameters • Intra-particle diffusion and tortuosity • Inter-particle dispersion and porosity • Stagnant mobile phase mass transfer • Spatial distribution in packed beds

  6. Relevance • (Bio)chromatography, ion exchange, and adsorption • Separation science, and technology • Groundwater flow and contaminant dispersion • Chemical engineering and bioreactor mass transfer • Column operation and compression technology

More Related